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Updated: Jan 27, 2026

The Lambda Select cII Mutation Detection System
Published on: April 26, 2018
Epistatic mutations under divergent selection govern phenotypic variation in the crow hybrid zone
Ulrich Knief1, Christen M Bossu2,3,4, Nicola Saino5
1Division of Evolutionary Biology, Faculty of Biology, LMU Munich, Munich, Germany.
Abstract:
The evolution of genetic barriers opposing interspecific gene flow is key to the origin of new species. Drawing from information on over 400 admixed genomes sourced from replicate transects across the European hybrid zone between all-black carrion crows and grey-coated hooded crows, we decipher the interplay between phenotypic divergence and selection at the molecular level. Over 68% of plumage variation was explained by epistasis between the gene NDP and a ~2.8-megabase region on chromosome 18 with suppressed recombination. Both pigmentation loci showed evidence for divergent selection resisting introgression. This study reveals how few, large-effect loci can govern prezygotic isolation and shield phenotypic divergence from gene flow.
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