Related Experiment Video
Updated: Jan 27, 2026

Author Spotlight: Development of a Novel Finite Element Analysis Model for Improved Orthognathic Surgical Techniques
Published on: October 20, 2023
Rapid maxillary expansion effects of nasal airway in children with cleft lip and palate using computational fluid
Tomonori Iwasaki1, Ayaka Yanagisawa-Minami1, Hokuto Suga1
1Department of Pediatric Dentistry, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima-City, Japan.
Insights
Rapid maxillary expansion (RME) significantly improved nasal airway ventilation in children with unilateral cleft lip and palate (UCLP). RME increased airflow and cross-sectional area on the cleft side, reducing nasal obstruction.
Area of Science:
- Orthodontics
- Pediatric Dentistry
- Craniofacial Surgery
Background:
- Rapid maxillary expansion (RME) enhances nasal ventilation in non-cleft children.
- Unilateral cleft lip and palate (UCLP) is associated with nasal obstruction and increased risk of sleep apnea.
- The impact of RME on nasal ventilation in UCLP patients remains unclear.
Purpose of the Study:
- To evaluate RME-induced changes in nasal airway ventilation parameters in UCLP children.
- To assess the effects of RME on airflow, air pressure, air velocity, and nasal cross-sectional area (CSA) in UCLP patients.
Main Methods:
- Retrospective analysis of 19 UCLP patients undergoing RME.
- Cone-beam computed tomography (CBCT) scans before and after RME.
- Computational fluid dynamics (CFD) analysis of nasal airway ventilation parameters.
Main Results:
- RME significantly reduced maximum pressure, air velocity, and nasal resistance in UCLP patients.
- Airflow rate and nasal CSA on the cleft side significantly increased post-RME.
- CFD analysis revealed substantial improvements in nasal ventilation.
Conclusions:
- RME effectively improves nasal ventilation in children with UCLP.
- Increased airflow and CSA on the cleft side contribute to enhanced nasal breathing.
- RME is a valuable intervention for managing nasal obstruction in UCLP.
Objectives:
Rapid maxillary expansion (RME) improves nasal airway ventilation in non-cleft palate children. Children with unilateral cleft lip and palate (UCLP) may have nasal obstruction and experience an increased risk of obstructive sleep apnoea. The effect of RME in UCLP children is unclear. This retrospective study evaluated RME-induced changes in ventilation parameters in children with UCLP using computational fluid dynamics.
Setting And Sample Population:
Nineteen patients (10 boys, mean age 10.7 years) who required RME had cone-beam computed tomography images taken before and after RME. Twenty control participants (11 boys, mean age 11.1 years) received regular orthodontic treatment.
Methods:
Nasal airway ventilation parameters (air pressure, air velocity and airflow rate) were analysed via computational fluid dynamics, and nasal cross-sectional area (CSA) was measured.
Results:
Maximum pressure, velocity and nasal resistance were significantly reduced by RME in the UCLP group. Air flow rate and CSA on the cleft side significantly were increased by RME in the UCLP group.
Conclusions:
In children with UCLP, increasing the quantity of airflow and CSA on the cleft side by RME substantially improved nasal ventilation.
More Related Videos
Related Concept Videos
Nose and Nasal Cavity
Heat and Free Expansion
Suctioning the Oropharyngeal Airway
After assembling the equipment, the nurse should practice hand hygiene and don appropriate PPE according to infection control guidelines to avoid the...
Suctioning the Nasopharyngeal Airway
Equipment Required
Administering Oxygen by Nasal Cannula
Nasal Cannulas
A nasal cannula is a lightweight tube split into two prongs placed in the nostrils,...
Thermal Expansion

