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Polyelectrolyte complex from cationized casein and sodium alginate for fragrance controlled release
Yuanxia Zhang1, Jianzhong Ma2, Qunna Xu2
1College of Bioresources Chemical and Materials Engineering, Shaanxi University of Science & Technology, Xi'an, 710021, PR, China; National Demonstration Center for Experimental Light Chemistry Engineering Education, Shaanxi University of Science and Technology, Xi'an, 710021, PR, China.
Colloids and Surfaces. B, Biointerfaces
|March 27, 2019
Summary
Novel casein (CA) and sodium alginate (NaAlg) polyelectrolyte complexes (PECs) were developed for controlled vanillin release. These microcapsules offer enhanced stability and sustained fragrance delivery for various applications.
Area of Science:
- Materials Science
- Polymer Chemistry
- Drug Delivery Systems
Background:
- Controlled release systems are crucial for enhancing product stability and efficacy.
- Polyelectrolyte complexes (PECs) offer versatile platforms for encapsulation and delivery.
- Fragrance delivery requires stable matrices that prevent premature volatilization.
Purpose of the Study:
- To design and characterize novel casein/sodium alginate (CA/NaAlg) polyelectrolyte complexes (PECs) for controlled vanillin release.
- To investigate the structural and morphological changes upon vanillin encapsulation.
- To evaluate the encapsulation efficiency, loading capacity, and in vitro release profile of vanillin from the PECs.
Main Methods:
- Fabrication of CA/NaAlg PECs via electrostatic interactions.
- Structural analysis using UV-Vis, Fourier Transform Infrared (FTIR), and X-ray Diffraction (XRD).
- Morphological characterization by Transmission Electron Microscopy (TEM).
- Thermal stability assessment using Thermogravimetric Analysis (TGA).
- In vitro release studies to determine sustained release characteristics.
Main Results:
- Spherical CA/NaAlg PEC microcapsules were successfully synthesized.
- Encapsulation of vanillin within the PEC matrix enhanced its thermal stability.
- Vanillin encapsulation efficiency was 41.39% and loading efficiency was 19.83%.
- In vitro studies demonstrated a sustained release profile for vanillin.
- Structural analysis confirmed successful formation of the PEC and vanillin loading.
Conclusions:
- CA/NaAlg PECs provide a feasible and effective microencapsulation strategy for controlled fragrance release.
- The developed system offers enhanced vanillin stability and sustained delivery.
- This technology holds significant potential for applications in food packaging, cosmetics, and textiles.
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