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Related Experiment Videos

A hypothesis on the primate neocortex evolution: column-multiplication hypothesis.

T Sawaguchi, K Kubota

    The International Journal of Neuroscience
    |August 1, 1986
    PubMed
    Summary

    The primate neocortex likely expanded through the multiplication of cortical columns, not changes in column size. This evolutionary hypothesis explains neocortical area growth and predicts specific column characteristics.

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    Area of Science:

    • Neuroscience
    • Evolutionary Biology
    • Comparative Anatomy

    Background:

    • The primate neocortex exhibits significant expansion in sensory, motor, and associational areas during evolution.
    • Understanding the microstructural basis of neocortical expansion is crucial for evolutionary neuroscience.

    Purpose of the Study:

    • To propose and explore the hypothesis that neocortical evolution in primates is driven by the multiplication of cortical columns.
    • To provide an explanatory framework for the observed expansion of neocortical areas.

    Main Methods:

    • Comparative analysis of primate neocortical structure.
    • Hypothetical modeling of evolutionary expansion mechanisms.

    Main Results:

    • The hypothesis posits that consistent cortical column size across primate species suggests multiplication as the primary expansion mechanism.

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  • This model accounts for the development of diverse sensory-motor and associational areas.

    • Conclusions:

    • The multiplication of cortical columns offers a parsimonious explanation for primate neocortical evolution.
    • The hypothesis predicts the existence of evolutionarily neutral columns, genetic regulation of columns, and intraspecies variations.