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Updated: Jan 27, 2026

Murine Renal Transplantation Procedure
Published on: July 10, 2009
Trichodysplasia spinulosa mimicking lichen nitidus in a renal transplant patient
Hope Barone1, Ross Brockman2, Luke Johnson2
1University of New England College of Osteopathic Medicine, Biddeford, Maine.
Abstract:
Trichodysplasia spinulosa (TS) is a rare cutaneous condition associated with the TSPyV and characterized by skin-colored, folliculocentric papules with keratin spicule formation. TS is seen almost exclusively in immunosuppressed individuals, often presenting in patients with a history of solid organ transplantation or chemotherapy for a lymphoreticular malignancy. We report a case of widespread TS in a 9-year-old girl with a history of renal transplantation complicated by BK viremia, which is also caused by a polyomavirus, BKPyV. The clinical presentation of TS in this case morphologically resembled the more common, harmless skin condition known as "lichen nitidus," and was more extensive than expected for TS, creating a diagnostic challenge. This case illustrates an important presentation of severe TS of which transplant teams, oncologists, primary care providers, and dermatologists should be aware.
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