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Sample Preparation to Bioinformatics Analysis of DNA Methylation: Association Strategy for Obesity and Related Trait Studies
Published on: May 6, 2022
Associations between Adipokines in Arthritic Disease and Implications for Obesity
Iona J MᵃᶜDonald1, Shan-Chi Liu2,3, Chien-Chung Huang4,5
1Graduate Institute of Basic Medical Science, China Medical University, Taichung 40402, Taiwan. ionamac@gmail.com.
Abstract:
Secretion from adipose tissue of adipokines or adipocytokines, comprising of bioactive peptides or proteins, immune molecules and inflammatory mediators, exert critical roles in inflammatory arthritis and obesity. This review considers the evidence generated over the last decade regarding the effects of several adipokines including leptin, adiponectin, visfatin, resistin, chemerin and apelin, in cartilage and bone homeostasis in the pathogenesis of rheumatoid arthritis and osteoarthritis, which has important implications for obesity.
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