Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Silicosis in the Artificial Stone Countertop Industry: An Official American Thoracic Society Workshop Report.

Annals of the American Thoracic Society·2026
Same author

From Feminist Activism to Academia? Fifty Years of Research on Gender-Based Violence in France.

Violence against women·2026
Same author

Phenotype-Genotype Correlations in ABCA3 Patients-The RespiRare Cohort.

Pediatric pulmonology·2025
Same author

Pediatric pituitary adenomas: clinical features, treatment strategies, and management challenges.

Endocrine·2025
Same author

The RaDiCo information system for rare disease cohorts.

Orphanet journal of rare diseases·2025
Same author

The Banning of Engineered Stone in Australia: An Evidence-Based and Precautionary Policy.

International journal of social determinants of health and health services·2025

Related Experiment Video

Updated: Jan 27, 2026

Human Lung Dendritic Cells: Spatial Distribution and Phenotypic Identification in Endobronchial Biopsies Using Immunohistochemistry and Flow Cytometry
11:02

Human Lung Dendritic Cells: Spatial Distribution and Phenotypic Identification in Endobronchial Biopsies Using Immunohistochemistry and Flow Cytometry

Published on: January 20, 2017

9.6K

Paediatric sarcoidosis.

Nadia Nathan1, Chiara Sileo2, Alain Calender3

  • 1Service de Pneumologie Pédiatrique et Centre de référence des maladies respiratoires rares, AP-HP, Hôpital Trousseau, Unité INSERM UMR-S933, Sorbonne Université, Paris, France.

Paediatric Respiratory Reviews
|March 29, 2019
PubMed
Summary
This summary is machine-generated.

Paediatric sarcoidosis, a rare granulomatous inflammation in children, often presents with general symptoms. This review summarizes current knowledge on its presentation, management, and evolution in this population.

Keywords:
ChildrenGranulomaInterstitial lung diseaseSarcoidosis

More Related Videos

Author Spotlight: Advancements in 3D Optical Imaging for Comprehensive Body Composition Assessment in Modern Research
06:48

Author Spotlight: Advancements in 3D Optical Imaging for Comprehensive Body Composition Assessment in Modern Research

Published on: June 7, 2024

2.1K
Candidate Gene Testing in Clinical Cohort Studies with Multiplexed Genotyping and Mass Spectrometry
05:53

Candidate Gene Testing in Clinical Cohort Studies with Multiplexed Genotyping and Mass Spectrometry

Published on: June 21, 2018

10.6K

Related Experiment Videos

Last Updated: Jan 27, 2026

Human Lung Dendritic Cells: Spatial Distribution and Phenotypic Identification in Endobronchial Biopsies Using Immunohistochemistry and Flow Cytometry
11:02

Human Lung Dendritic Cells: Spatial Distribution and Phenotypic Identification in Endobronchial Biopsies Using Immunohistochemistry and Flow Cytometry

Published on: January 20, 2017

9.6K
Author Spotlight: Advancements in 3D Optical Imaging for Comprehensive Body Composition Assessment in Modern Research
06:48

Author Spotlight: Advancements in 3D Optical Imaging for Comprehensive Body Composition Assessment in Modern Research

Published on: June 7, 2024

2.1K
Candidate Gene Testing in Clinical Cohort Studies with Multiplexed Genotyping and Mass Spectrometry
05:53

Candidate Gene Testing in Clinical Cohort Studies with Multiplexed Genotyping and Mass Spectrometry

Published on: June 21, 2018

10.6K

Area of Science:

  • Pediatrics
  • Immunology
  • Rare Diseases

Background:

  • Paediatric sarcoidosis is a rare granulomatous inflammatory disease with an estimated incidence of 0.6-1.02/100,000 children.
  • The exact pathophysiologic basis remains unclear, with current hypotheses involving genetic predisposition and environmental factors.
  • Unlike adult forms, general symptoms frequently dominate the clinical presentation at diagnosis in children.

Purpose of the Study:

  • To provide a comprehensive overview of paediatric sarcoidosis.
  • To summarize available data on the presentation, management, and evolution of sarcoidosis in children.
  • To highlight the multi-organ nature of the disease, commonly affecting lungs, lymphatic system, and liver.

Main Methods:

  • Literature review of cohort studies on paediatric sarcoidosis.
  • Synthesis of data regarding disease presentation, clinical course, and therapeutic strategies.
  • Analysis of epidemiological data and etiological hypotheses.

Main Results:

  • Paediatric sarcoidosis is a multi-organ disorder, with lungs, lymphatic system, and liver being preferentially affected.
  • General systemic symptoms are common presenting features in children.
  • Data on incidence may be underestimated due to the lack of international registries.

Conclusions:

  • Paediatric sarcoidosis requires a thorough understanding of its unique presentation and multi-systemic involvement.
  • Further research and international collaboration are needed to improve diagnosis and management.
  • This review consolidates current knowledge to guide clinicians and researchers in managing this rare condition.