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Updated: Jan 27, 2026

A Data-Driven Approach to Quantifying Immune States in Sepsis
Published on: February 7, 2025
[Surviving Sepsis Campaign update 2018: the 1 h bundle : Background to the new recommendations]
1Klinik für Anästhesiologie, Klinikum der Universität München, Marchioninistraße 15, 81377, München, Deutschland. Josef.Briegel@med.uni-muenchen.de.
The Surviving Sepsis Campaign (SSC) updated its sepsis bundle in 2018, consolidating previous guidelines into a single 1-hour bundle. This new approach emphasizes prompt diagnostic and therapeutic actions within one hour of sepsis recognition.
Area of Science:
- Critical Care Medicine
- Infectious Diseases
- Emergency Medicine
Background:
- The Surviving Sepsis Campaign (SSC) previously issued 3-hour and 6-hour sepsis bundles.
- Sepsis management requires timely and coordinated interventions.
Purpose of the Study:
- To present the background of the updated Surviving Sepsis Campaign (SSC) sepsis bundle.
- To discuss the criticisms and implications of the new 1-hour sepsis bundle.
Main Methods:
- Review of the Surviving Sepsis Campaign (SSC) April 2018 guidelines.
- Analysis of the restructuring and consolidation of previous sepsis bundles.
- Discussion of diagnostic and therapeutic measures within the 1-hour timeframe.
Main Results:
- The 2018 update combines the original 3-hour and 6-hour sepsis bundles into a single 1-hour bundle.
- The new bundle focuses on critical actions within the first hour of sepsis recognition.
Conclusions:
- The 1-hour sepsis bundle represents a significant shift in guideline recommendations.
- Critical evaluation of the new bundle's background and potential challenges is necessary.
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