[How to promote the clinical study of transanal total mesorectal excision in China]

China has the largest group of patients with colorectal cancer in the world, but there are few international guidelines for the diagnosis and treatment of colorectal cancer from China, or evidence of high-level " evidence-based medicine" research in China. Transanal total mesorectal excision (taTME) is a new surgical procedure emerging in the field of colorectal surgery in recent years. taTME-related clinical research is almost simultaneously carried out in parallel with its clinical practice in the world. Based on the experience of Chinese TaTME Registry Collaborative and COLOR trials in colorectal surgery field, we aim to introduce how to organize and conduct COLOR III trial in China. To use the standardized clinical practice and clinical study of taTME surgery as an example, and promote it in colorectal surgery to realize the transformation to research-oriented disciplines, Chinese colorectal surgery has a long way to go.