Related Experiment Video
Updated: Jan 27, 2026

Robot-assisted Total Mesorectal Excision and Lateral Pelvic Lymph Node Dissection for Locally Advanced Middle-low Rectal Cancer
Published on: February 12, 2022
[Transanal total mesorectal excision and organ function preservation].
Zhanlong Shen1, Yingjiang Ye2, Long Zhao1
1Department of Gastroenterological Surgery, Laboratory of Surgical Oncology, Laboratory of General Surgery, Beijing Key Laboratory of Colorectal Cancer Diagnosis and Treatment Research, Peking University People's Hospital, Peking 100044, China.
Transanal total mesorectal excision (taTME) offers improved surgical field visualization and potential for nerve preservation. While early anal function may be affected, long-term outcomes are comparable to traditional methods, with benefits for urinary and sexual function.
Area of Science:
- Colorectal Surgery
- Minimally Invasive Surgery
- Surgical Oncology
Background:
- Transanal total mesorectal excision (taTME) utilizes endoscopic assistance and pelvic pneumoperitoneum.
- The transanal minimally invasive surgery (TAMIS) platform may reduce internal anal sphincter injury.
Purpose of the Study:
- To evaluate the oncological safety and nerve protection offered by taTME.
- To compare functional outcomes of taTME with transabdominal TME.
Main Methods:
- Review of current data comparing taTME and transabdominal TME.
- Analysis of factors influencing early postoperative anal function.
- Guidance for pelvic nerve and organ function preservation during taTME.
Main Results:
- taTME shows similar postoperative anal, urinary, and sexual function compared to transabdominal TME.
- Early anal function impairment may relate to the transanal approach, single port, and learning curve, but improves over time.
- Nerve protection during taTME requires familiarity with pelvic anatomy and careful dissection.
Conclusions:
- taTME is distinct from NOTES, prioritizing oncological safety and nerve protection.
- Combining transanal and transabdominal approaches can enhance surgical quality and organ function preservation.
More Related Videos
Related Concept Videos
Base Excision Repair
The first step of...
Base Excision Repair
Nucleotide Excision Repair
Nucleotide Excision Repair
Cells are regularly exposed to mutagens—factors in the environment that can damage DNA and generate mutations. UV radiation is one of the most common mutagens and is estimated to introduce a significant number of changes in DNA. These include bends or kinks in the structure, which can block DNA replication or transcription. If these errors are not fixed, the damage can cause mutations, which in turn can result in cancer or disease depending on which sequences are...
Organic Compounds
Levels of Organization
Molecules Are Composed of Atoms, and Biomolecules Are Assembled from Molecules:
The most basic levels include atoms, molecules, and biomolecules. Atoms, the smallest unit of ordinary matter, are composed of a nucleus and electrons. Molecules...

