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Related Experiment Video

Updated: Jan 27, 2026

Measurement of Carotenoids in Perifovea using the Macular Pigment Reflectometer

Measurement of Carotenoids in Perifovea using the Macular Pigment Reflectometer

Published on: January 29, 2020

[Acute Macular Neuroretinopathy].

Anja Wyss^1,2, Reinhard Rüesch¹, Nicole Schwizer¹

¹Augenklinik, Kantonsspital St. Gallen, Schweiz.

Klinische Monatsblatter Fur Augenheilkunde

|March 29, 2019

Summary

Acute macular neuroretinopathy (AMNR) presents as sudden vision loss in young women. This study shows AMNR lesions are best seen with infrared imaging and often improve with observation.

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Area of Science:

Ophthalmology
Retinal Diseases
Medical Imaging

Background:

Acute macular neuroretinopathy (AMNR) is a rare macular disorder.
Typically affects young women with sudden central vision loss (scotomas).
Lesions are often reddish-brown, best visualized with infrared reflectance imaging.

Observation:

A retrospective case series of 4 young women diagnosed with AMNR.
Clinical and morphological features were analyzed using various imaging techniques.
Patients presented with central visual field defects, sometimes bilateral, and often a history of flu-like illness.

Findings:

Visual acuity was generally preserved (1.0) despite central scotomas.
Retinal lesions were subtle, primarily detected via infrared reflectance imaging and optical coherence tomography (OCT).
OCT revealed focal abnormalities in the photoreceptor outer segments, with symptoms improving over 9-36 months.

Implications:

AMNR presents with acute central scotomas and mild visual acuity impact.
Prognosis varies, with some cases resolving spontaneously and others leading to persistent vision reduction.
Due to the lack of causative treatment, an observational approach is recommended for AMNR management.