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Adherence in Hypertension

Michel Burnier1, Brent M Egan2

  • 1From the Service of Nephrology and Hypertension, Department of Medicine, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland (M.B.).

Circulation Research
|March 29, 2019
PubMed

Insights

Poor adherence to hypertension medication is a major cause of uncontrolled blood pressure. Addressing patient adherence is crucial for managing hypertension effectively and reducing cardiovascular risks.

Area of Science:

  • Cardiology
  • Public Health
  • Pharmacology

Background:

  • Hypertension is a leading global cause of noncommunicable disease deaths, largely uncontrolled worldwide.
  • Suboptimal adherence to pharmacotherapy significantly contributes to poor blood pressure control in hypertensive patients.
  • Adherence issues encompass failure to initiate, maintain, or persist with prescribed antihypertensive medications.

Purpose of the Study:

  • To highlight the critical role of adherence in hypertension management.
  • To identify factors contributing to medication nonadherence in hypertension.
  • To emphasize the importance of addressing adherence in clinical practice and guidelines.

Main Methods:

  • Review of factors associated with medication nonadherence in hypertension.
  • Discussion of monitoring strategies for adherence in high-risk patients.
  • Analysis of current approaches to improve adherence in hypertension management.

Main Results:

  • Multiple factors (demographic, socioeconomic, medical, therapy-related, healthcare system, patient-specific) are linked to nonadherence.
  • Electronic and biochemical monitoring can detect and improve adherence in high-risk individuals.
  • Focusing on adherence is essential given the lack of new antihypertensive drugs.

Conclusions:

  • Understanding adherence barriers is key to managing hypertension.
  • Enhanced monitoring and accessibility of adherence measures offer future opportunities.
  • Healthcare providers must prioritize drug adherence as a major component of hypertension management.

Keywords:
blood pressurecardiovascular diseasesdrug monitoringhypertensionprevalenceresistant hypertension

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