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An evaluation of the efficacy and irritability of Sporicidin as a hand dip

R D Holderman, H L Parlette, G T Terezhalmy

    Oral Surgery, Oral Medicine, and Oral Pathology
    |August 1, 1986
    PubMed

    Insights

    Sporicidin disinfectant hand dip significantly reduced microbial counts. However, skin irritation, sensitivity, yellowing, and odor may limit its widespread clinical application.

    Area of Science:

    • Microbiology
    • Dermatology
    • Infectious Disease Control

    Background:

    • Healthcare-associated infections necessitate effective hand hygiene protocols.
    • Antimicrobial efficacy and skin compatibility are crucial for topical disinfectants.

    Purpose of the Study:

    • To evaluate the antimicrobial efficacy of diluted Sporicidin as a hand disinfectant.
    • To assess potential adverse dermal effects associated with Sporicidin use.

    Main Methods:

    • Sporicidin was diluted 1:16 and used as a hand dip.
    • Microbial colony-forming units were quantified on control and treated hands.

    Main Results:

    • A substantial reduction in mean colony-forming units was observed with Sporicidin treatment.
    • Adverse effects included dermal irritation, sensitivity, skin yellowing, and an objectionable odor.

    Conclusions:

    • Diluted Sporicidin exhibits antimicrobial efficacy for hand disinfection.
    • Dermal side effects and odor may restrict its routine clinical use.

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