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Updated: Jan 27, 2026

Quantifying Vibrio cholerae Colonization and Diarrhea in the Adult Zebrafish Model
Published on: July 12, 2018
Non-O1 Vibrio cholerae in Shellfish, Sediment and Waters of the U.S. Gulf Coast
A DePAOLA1, M W Presnell1, M L Motes1
1Gulf Coast Technical Services Unit, Food and Drug Administration, Dauphin Island, Alabama 36528 and Division of Microbiology, Food and Drug Administration, 1090 Tusculum Avenue, Cincinnati, Ohio 45226.
Abstract:
In a study conducted throughout U.S. Gulf Coastal waters, Vibrio cholerae non-O1 was isolated more frequently from water samples than from shellfish or sediment samples. Frequency of V. cholerae recovery was directly related to water temperature and inversely related to salinity. The presence of V. cholerae was not adequately indicated by the fecal coliform standards for shellfish-growing waters and market shellfish as established by the National Shellfish Sanitation Program. Although all cultures tested by the Y-1 mouse adrenal cell assay or by radioimmunoassay for production of a cholera toxin-like toxin were negative, 4 of 13 isolates caused diarrhea in the infant rabbit.
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