Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Seedless Vascular Plants

Seedless Vascular Plants

Seedless Vascular Plants Were the First Tall Plants on Earth

Molecular Models

Molecular Models

Physical models representing molecular architectures of chemical compounds play essential roles in understanding chemistry. The use of molecular models makes it easier to visualize the structures and shapes of atoms and molecules.

Molecular and Ionic Solids

Molecular and Ionic Solids

Crystalline solids are divided into four types: molecular, ionic, metallic, and covalent network based on the type of constituent units and their interparticle interactions.
Molecular Solids
Molecular crystalline solids, such as ice, sucrose (table sugar), and iodine, are solids that are composed of neutral molecules as their constituent units. These molecules are held together by weak intermolecular forces such as London dispersion forces, dipole-dipole interactions, or hydrogen bonds, which...

Molecular Orbital Theory II

Molecular Orbital Theory II

Molecular Orbital Energy Diagrams

Molecular Orbital Theory I

Molecular Orbital Theory I

Overview of Molecular Orbital Theory

Predicting Molecular Geometry

Predicting Molecular Geometry

VSEPR Theory for Determination of Electron Pair Geometries

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

An International, Multi-Specialty Consensus Document on the Optimal Management of Patients with Internal Carotid Artery Occlusion.

Journal of vascular surgery·2026

Same author

Risk Factors for Delirium after Abdominal Aortic Aneurysm Repair.

Annals of vascular surgery·2026

Same author

Optimal treatment of preclinical cardiovascular disease: A narrative review with a focus on carotid artery stenosis.

Seminars in vascular surgery·2026

Same author

Skeletal Muscle Mass and Quality in Peripheral Artery Disease: New Insights into Clinical Management and Therapeutic Optimization.

Annals of vascular surgery·2026

Same author

From Acute Thrombosis to Eccentric Neointima in Arteriovenous Fistula.

Seminars in thrombosis and hemostasis·2026

Same author

Aortotomy-induced acute mural thrombosis progresses to saccular aneurysm formation.

Research and practice in thrombosis and haemostasis·2026

Same journal

Self-Expandable versus Balloon-Expandable Bridging Stents in Off-the-Shelf Inner Branch Repair: Midterm Results from the INBREED Registry.

Journal of vascular surgery·2026

Same journal

Procedural outcomes and follow-up of endovascular treatment for extracranial carotid artery aneurysms; a systematic review.

Journal of vascular surgery·2026

Same journal

Impact of Insurance Status on Urgency of Presentation and Perioperative Outcomes Following Endovascular Repair of Abdominal Aortic Aneurysms: A Vascular Quality Initiative Analysis.

Journal of vascular surgery·2026

Same journal

Large language models routinely overcode peripheral endovascular procedures relative to professional coders.

Journal of vascular surgery·2026

Same journal

Comparison of Deep and Non-Deep Hypothermia in Thoracic and Thoracoabdominal Aortic Surgery: A Systematic Review and Meta-Analysis.

Journal of vascular surgery·2026

Same journal

Horner Syndrome Secondary to Giant Shamblin Type III Carotid Body Tumor.

Journal of vascular surgery·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Jan 27, 2026

A Patient-Derived Xenograft Model for Venous Malformation

A Patient-Derived Xenograft Model for Venous Malformation

Published on: June 15, 2020

Molecular changes associated with vascular malformations.

Arash Fereydooni¹, Alan Dardik², Naiem Nassiri²

¹Yale University School of Medicine, New Haven, Conn.

Journal of Vascular Surgery

|March 30, 2019

Summary

This summary is machine-generated.

Genetic mutations in vascular malformations are linked to specific signaling pathways. Targeting these pathways offers new therapeutic strategies for vascular anomalies.

Keywords:

Congenital disorders Rapamycin Vascular anomaly Vascular malformation mTOR pathway

More Related Videos

Induction and Micro-CT Imaging of Cerebral Cavernous Malformations in Mouse Model

Induction and Micro-CT Imaging of Cerebral Cavernous Malformations in Mouse Model

Published on: September 4, 2017

Comprehensive Endovascular and Open Surgical Management of Cerebral Arteriovenous Malformations

Comprehensive Endovascular and Open Surgical Management of Cerebral Arteriovenous Malformations

Published on: October 20, 2017

Related Experiment Videos

Last Updated: Jan 27, 2026

A Patient-Derived Xenograft Model for Venous Malformation

A Patient-Derived Xenograft Model for Venous Malformation

Published on: June 15, 2020

Induction and Micro-CT Imaging of Cerebral Cavernous Malformations in Mouse Model

Induction and Micro-CT Imaging of Cerebral Cavernous Malformations in Mouse Model

Published on: September 4, 2017

Comprehensive Endovascular and Open Surgical Management of Cerebral Arteriovenous Malformations

Comprehensive Endovascular and Open Surgical Management of Cerebral Arteriovenous Malformations

Published on: October 20, 2017

Area of Science:

Vascular biology and genetics
Molecular mechanisms of disease
Medical and surgical treatment of vascular anomalies

Background:

Vascular anomalies are broadly categorized into tumors and malformations.
Somatic mosaic gene mutations are the primary cause of most vascular malformations.
Genetic research has elucidated key biomolecular pathways in pathogenesis.

Purpose of the Study:

To review the updated International Society for Study of Vascular Anomalies classification.
To highlight potential therapeutic targets based on genetic findings.
To provide vascular surgeons with an updated perspective on etiologies.

Main Methods:

Literature review of current research on vascular anomalies.
Analysis of genetic mutations and associated signaling pathways.
Integration of updated classification systems.

Main Results:

Vascular malformations are linked to specific genetic mutations.
RAS/MAPK/ERK pathway mutations are associated with fast-flow arteriovenous malformations.
PI3K/AKT/mTOR pathway mutations are associated with slow-flow venous and lymphatic malformations.

Conclusions:

Understanding the genetic basis of vascular malformations informs targeted therapies.
Therapeutic strategies should focus on the specific mutated etiological pathways.
This knowledge facilitates multidisciplinary collaboration for improved patient care.