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Related Concept Videos

Mitral Regurgitation I: Introduction01:20

Mitral Regurgitation I: Introduction

494
Mitral regurgitation is characterized by the backward circulation of blood from the left ventricle to the left atrium during systole, a phase of the cardiac cycle when the heart contracts and pumps blood out of the chambers. This abnormal flow occurs primarily due to the dysfunction of the mitral valve or its supporting structures, which include the mitral leaflets, chordae tendineae, annulus, and papillary muscles.Etiology and Mechanisms:Primary Mitral Regurgitation: This type arises from...
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Mitral Regurgitation III: Medical Management01:25

Mitral Regurgitation III: Medical Management

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Mitral regurgitation (MR) is characterized by retrograde blood circulation from the left ventricle into the left atrium due to inadequate mitral valve closure. The severity of the condition, symptoms, and underlying cause determine treatment strategies.Monitoring and Pharmacological TreatmentPatients with mild to moderate MR typically do not need immediate intervention but regular monitoring to assess progression and guide treatment. Patients with mild MR should have an echocardiogram every 3-5...
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Mitral Regurgitation II: Clinical Features and Diagnostic Tests01:23

Mitral Regurgitation II: Clinical Features and Diagnostic Tests

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Mitral regurgitation (MR) is a valvular heart disorder in which the mitral valve fails to close tightly, allowing blood to leak backward into the heart. Understanding the clinical manifestations, assessment, diagnostic findings, and medical management of MR is crucial to effectively managing affected patients.Clinical Manifestations of Mitral RegurgitationMitral regurgitation can be acute or chronic, each presenting differently and requiring different approaches:1. Acute Mitral...
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Mitral Regurgitation IV: Nursing Management01:28

Mitral Regurgitation IV: Nursing Management

331
Mitral regurgitation (MR) is a condition where the mitral valve does not close properly, leading to the backward flow of blood from the left ventricle into the left atrium during systole. This condition can arise from various causes, including rheumatic fever, infective endocarditis, or degenerative valve disease. Effective nursing management is crucial to optimizing patient outcomes and involves comprehensive assessment and targeted interventions.Comprehensive Patient AssessmentA detailed...
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Papillary Dermis01:11

Papillary Dermis

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Dermis
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
Papillary Layer
The papillary layer is made of loose, areolar connective tissue, which means the collagen...
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Mismatch Repair01:36

Mismatch Repair

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Overview
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Related Experiment Video

Updated: Jan 27, 2026

A Simplified Stepwise Approach to Echo Guidance during Percutaneous Mitral Valve Repair
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[Mitral Regurgitation Repaired by Papillary Heads Optimization Technique].

Shuji Nagatomi1, Kazuhisa Matsumoto, Kousuke Mukaihara

  • 1Department of Cardiovascular Surgery, Kagoshima University Hospital, Kagoshima, Japan.

Kyobu Geka. the Japanese Journal of Thoracic Surgery
|March 30, 2019
PubMed
Summary

Functional mitral regurgitation (FMR) repair using papillary heads optimization (PHO) showed early success but late recurrence in one dilated cardiomyopathy case. Careful consideration of PHO for DCM is needed.

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An Image Guided Transapical Mitral Valve Leaflet Puncture Model of Controlled Volume Overload from Mitral Regurgitation in the Rat
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Area of Science:

  • Cardiovascular Surgery
  • Cardiac Surgery Techniques
  • Mitral Valve Repair

Background:

  • Functional mitral regurgitation (FMR) increases mortality and heart failure incidence.
  • Mitral valve (MV) reconstruction offers advantages over replacement, avoiding anticoagulation and preserving left ventricular function.
  • Restrictive mitral valve annuloplasty alone has shown high recurrence rates for FMR.

Observation:

  • Papillary heads optimization (PHO) is a reconstructive technique for FMR.
  • MV repair with PHO was performed in three FMR cases: one chronic MR with tethering/dilatation, and two due to ischemic and dilated cardiomyopathy (DCM).
  • Early postoperative success was achieved in all cases, but moderate MR recurred in the DCM case after 9 months.

Findings:

  • Transthoracic echocardiography revealed increased distance between papillary muscle origin and posterior MV annulus in the recurrent case.
  • The recurrence suggests PHO's effectiveness may be limited in the context of progressive DCM.
  • Papillary muscle position correction might be overcome by DCM progression, leading to MR recurrence.

Implications:

  • The PHO technique shows promise for FMR but requires careful patient selection, particularly in cases of dilated cardiomyopathy.
  • Further research is needed to refine indications for PHO in DCM patients to prevent late MR recurrence.
  • Optimizing surgical strategies for FMR in DCM is crucial for long-term patient outcomes.