Related Experiment Video
Updated: Jan 27, 2026

Mass Spectrometry-Guided Genome Mining as a Tool to Uncover Novel Natural Products
Published on: March 12, 2020
A Strategy toward Icetexane Natural Products
Daniel J Moon1, Mohammad Al-Amin1, Robert S Lewis1
1Department of Chemistry & Biochemistry, University of Delaware, Newark, DE 19176, United States.
Abstract:
Icetexane diterpenoids are richly complex polycyclic natural products that have been described with a variety of biological activities. We report here a general synthetic approach toward the 6-7-6 tricyclic core structure of these interesting synthetic targets based on a two-step enolate alkylation and ring-closing metathesis reaction sequence.
Related Concept Videos
What is Natural Selection?
Nature and Nurture
Persuasion Strategies
The Wave Nature of Light
Chirality in Nature
Limits to Natural Selection

