Graves' disease and selective resistance of pituitary thyrotroph to thyroid hormone. A case report

A patient with Graves' disease who had inappropriately increased thyroid stimulating hormone (TSH) concentrations and TSH response to thyrotrophin-releasing hormone is reported. No pituitary tumour could be demonstrated and the patient is considered to be an example of selective resistance of the pituitary thyrotroph to thyroid hormone action.