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Updated: Jan 27, 2026

Targeting the Rat's Small Bowel: Long-Term Infusion into the Superior Mesenteric Artery
Published on: April 8, 2021
A modified endovascular technique for treating spontaneous isolated superior mesenteric artery dissection and the
Jiale Ou1, Hongyao Hu1, Zhenzhong Wu1
1Division of Interventional Radiology, Department of Radiology, Renmin Hospital of Wuhan University, Wuhan, 430000, China.
Purpose:
The spontaneous isolated dissection of superior mesenteric artery (SIDSMA) is a rare medical condition and the treatment remains controversial. This study is to present our refined technique with a Flexor introducer to facilitate stent advancement and its early to medium-term outcomes.
Methods:
A total of 16 patients diagnosed with SIDSMA and repaired with endovascular stenting from January 2012 to December 2017 were retrospectively identified. All patients were male, and the average age was 56 years old (range from 48 to 72 years old). Diagnosis was preoperatively confirmed using computed tomography angiography and their morphologic features were measured. A long Flexor introducer was delivered to the true lumen of dissected superior mesenteric artery prior to coaxially advancing a stent. Patient demographics, endovascular procedures and postoperative outcomes were collected for analysis.
Results:
Total technical success was 87.5%. Endovascular attempt was unsuccessful in two patients with extensive thrombus, and the guidewire failed to pass through the true lumen. The remaining 14 SMA dissections were successfully repaired with the modified method. Four patients were repaired using bare stents and 10 with covered stents. The average operative duration was 44 ± 18 minutes. Abdominal pain was relieved postoperatively in all cases except one patient with no identified reasons. The median follow-up duration was 17 months (2-63 months). No procedure- or dissection-related symptoms was present during follow up, and postoperative computed tomography angiography showed all stented SMAs were patent.
Conclusions:
Coaxial delivery of stents within the introducer can yield high technical success and good clinical outcomes in early to medium term. Extensive thrombus inside SIDSMA is the exclusive cause for endovascular failure with this technique.
Insights
This study presents a refined technique for treating spontaneous isolated dissection of the superior mesenteric artery (SIDSMA) using a Flexor introducer. The method achieved high technical success and positive early-to-medium term outcomes for SIDSMA repair.
Area of Science:
- Vascular Surgery
- Interventional Radiology
- Gastroenterology
Background:
- Spontaneous isolated dissection of the superior mesenteric artery (SIDSMA) is a rare condition with controversial treatment options.
- Endovascular stenting is a potential treatment modality for SIDSMA.
Purpose of the Study:
- To present a refined endovascular technique using a Flexor introducer for stent advancement in SIDSMA.
- To evaluate the early to medium-term outcomes of this refined technique.
Main Methods:
- Retrospective analysis of 16 male patients with SIDSMA treated with endovascular stenting (January 2012-December 2017).
- Diagnosis confirmed by computed tomography angiography.
- A Flexor introducer was used to facilitate coaxial stent delivery into the true lumen of the dissected superior mesenteric artery.
Main Results:
- Technical success rate of 87.5% (14 out of 16 patients).
- Successful stenting achieved in 14 cases; two failures due to extensive thrombus.
- All successfully stented superior mesenteric arteries remained patent at follow-up (median 17 months).
- Postoperative abdominal pain resolved in most patients.
Conclusions:
- Coaxial stent delivery with a Flexor introducer offers high technical success and favorable clinical outcomes for SIDSMA.
- Extensive thrombus is the primary factor limiting endovascular treatment success in SIDSMA.
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