Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Oxidation Numbers03:14

Oxidation Numbers

42.3K
In redox reactions, the transfer of electrons occurs between reacting species. Electron transfer is described by a hypothetical number called the oxidation number (or oxidation state). It represents the effective charge of an atom or element, which is assigned using a set of rules.
42.3K
Alkali Metals03:06

Alkali Metals

24.3K
Group 1 elements are soft and shiny metallic solids. They are malleable, ductile, and good conductors of heat and electricity. The melting points of the alkali metals are unusually low for metals and decrease going down the group, while the density increases going down the group with the exception of potassium (Table 1).
Table 1: Properties of the alkali metals
24.3K
Oxidation-Reduction Reactions03:11

Oxidation-Reduction Reactions

75.3K
Oxidation–Reduction Reactions
75.3K
Properties of Transition Metals02:58

Properties of Transition Metals

29.7K
Transition metals are defined as those elements that have partially filled d orbitals. As shown in Figure 1, the d-block elements in groups 3–12 are transition elements. The f-block elements, also called inner transition metals (the lanthanides and actinides), also meet this criterion because the d orbital is partially occupied before the f orbitals.
29.7K
Metal-Ligand Bonds02:51

Metal-Ligand Bonds

24.1K
The hemoglobin in the blood, the chlorophyll in green plants, vitamin B-12, and the catalyst used in the manufacture of polyethylene all contain coordination compounds. Ions of the metals, especially the transition metals, are likely to form complexes.
In these complexes, transition metals form coordinate covalent bonds, a kind of Lewis acid-base interaction in which both of the electrons in the bond are contributed by a donor (Lewis base) to an electron acceptor (Lewis acid). The Lewis acid in...
24.1K
Metallic Solids02:37

Metallic Solids

20.5K
Metallic solids such as crystals of copper, aluminum, and iron are formed by metal atoms. The structure of metallic crystals is often described as a uniform distribution of atomic nuclei within a “sea” of delocalized electrons. The atoms within such a metallic solid are held together by a unique force known as metallic bonding that gives rise to many useful and varied bulk properties.
All metallic solids exhibit high thermal and electrical conductivity, metallic luster, and malleability....
20.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Sustainable AFM-Based Nanolithography on Chitosan Thin Films for 2.5D and 3D Nanostructure Fabrication.

Nanomaterials (Basel, Switzerland)·2026
Same author

Chitosan Nanoparticles Unlock the Antioxidant Potential of Epigallocatechin Gallate in Pancreatic and Hepatic Cancer Cell Models.

ACS omega·2026
Same author

Structural and Physical Properties of Chitosan Films Containing UV-Driven <i>In Situ</i> Growth of Silver Nanoparticles.

ACS omega·2026
Same author

Nurses' Perspectives on the Non-Pharmacological Management of Oral Mucositis in Onco-Hematological Care: A Qualitative Content Analysis.

Nursing reports (Pavia, Italy)·2026
Same author

A critical guideline for controlling monocyte-derived macrophages phenotypes.

Frontiers in immunology·2026
Same author

Autosomal Dominant Hyper-IgE Syndrome Patients Retain IL10-Producing preTh17-Cells That Are Activated by Opportunistic Pathogens and Support IgE Production.

Allergy·2026

Related Experiment Video

Updated: Jan 27, 2026

Molten-Salt Synthesis of Complex Metal Oxide Nanoparticles
08:43

Molten-Salt Synthesis of Complex Metal Oxide Nanoparticles

Published on: October 27, 2018

18.8K

Tailoring Cell Morphomechanical Perturbations Through Metal Oxide Nanoparticles.

Valeria De Matteis1, Mariafrancesca Cascione2, Chiara Cristina Toma2

  • 1Dipartimento di Matematica e Fisica "Ennio De Giorgi", Università del Salento, Via Arnesano, 73100, Lecce, Italy. valeria.dematteis@unisalento.it.

Nanoscale Research Letters
|March 30, 2019
PubMed
Summary

Nanoparticle (NP) toxicity is not fully understood. This study shows how SiO2 and TiO2 NPs alter cell elasticity, revealing a link between NP properties, cell type, and mechanical changes, impacting cell health.

Keywords:
BiomechanicsCytoskeleton rearrangementsNanoparticlesToxicityYoung’s Modulus

More Related Videos

In Situ Detection and Single Cell Quantification of Metal Oxide Nanoparticles Using Nuclear Microprobe Analysis
14:53

In Situ Detection and Single Cell Quantification of Metal Oxide Nanoparticles Using Nuclear Microprobe Analysis

Published on: February 3, 2018

7.6K
Identification of Metal Oxide Nanoparticles in Histological Samples by Enhanced Darkfield Microscopy and Hyperspectral Mapping
12:19

Identification of Metal Oxide Nanoparticles in Histological Samples by Enhanced Darkfield Microscopy and Hyperspectral Mapping

Published on: December 8, 2015

12.9K

Related Experiment Videos

Last Updated: Jan 27, 2026

Molten-Salt Synthesis of Complex Metal Oxide Nanoparticles
08:43

Molten-Salt Synthesis of Complex Metal Oxide Nanoparticles

Published on: October 27, 2018

18.8K
In Situ Detection and Single Cell Quantification of Metal Oxide Nanoparticles Using Nuclear Microprobe Analysis
14:53

In Situ Detection and Single Cell Quantification of Metal Oxide Nanoparticles Using Nuclear Microprobe Analysis

Published on: February 3, 2018

7.6K
Identification of Metal Oxide Nanoparticles in Histological Samples by Enhanced Darkfield Microscopy and Hyperspectral Mapping
12:19

Identification of Metal Oxide Nanoparticles in Histological Samples by Enhanced Darkfield Microscopy and Hyperspectral Mapping

Published on: December 8, 2015

12.9K

Area of Science:

  • Nanotoxicology
  • Cellular Mechanics
  • Biophysics

Background:

  • Growing use of nanoparticles (NPs) in commerce necessitates understanding their toxicity.
  • Nano-bio interactions, particularly mechanical effects on cells, require further investigation.
  • Cellular mechanics, indicated by elasticity, are vital for cell functions.

Purpose of the Study:

  • To investigate the in vitro effects of SiO2 NPs and TiO2 NPs on the elasticity of Caco-2 and A549 cell lines.
  • To explore the correlation between NP physicochemical properties, cellular mechanical changes, and toxicity.
  • To understand how NP-cell interactions influence cellular mechanical properties.

Main Methods:

  • In vitro assessment of Young's modulus in Caco-2 and A549 cells exposed to SiO2 NPs and TiO2 NPs.
  • Analysis of morphological and morphometric changes in the actin network.
  • Evaluation of NP-induced perturbations in cell elasticity.

Main Results:

  • TiO2 NPs exhibited stronger effects on cell elasticity than SiO2 NPs.
  • TiO2 NPs induced significant changes in the actin network's morphology and morphometry.
  • TiO2 NPs increased elasticity in Caco-2 cells but decreased it in A549 cells.

Conclusions:

  • Cellular elasticity alterations correlate with NP toxicity.
  • The impact of NPs on cell mechanics is dependent on NP physicochemical properties and cell type.
  • This study highlights the importance of mechanical viewpoints in nanotoxicology.