Left atrial volume index and left ventricular global longitudinal strain predict new-onset atrial fibrillation in

Kenneth Bruun Pedersen1, Charlotte Madsen2, Niels Christian Foldager Sandgaard3

  • 1Department of Cardiology, Odense University Hospital, Sdr. Boulevard 29, 5000, Odense C, Odense, Denmark. KennethBruunPedersen@gmail.com.

Insights

Echocardiography can predict atrial fibrillation (AF) in patients with transient ischemic attack (TIA). Larger left atrial volumes and depressed left ventricular function identified via echocardiography may indicate AF risk.

Area of Science:

  • Cardiology
  • Neurology
  • Medical Imaging

Background:

  • Atrial fibrillation (AF) is a common arrhythmia that increases stroke risk.
  • Transient ischemic attack (TIA) is a warning sign for future stroke, often associated with AF.
  • Non-invasive methods to predict AF in TIA patients are crucial for timely intervention.

Purpose of the Study:

  • To investigate echocardiographic parameters for predicting AF in TIA patients.
  • To assess the relationship between left atrial (LA) and left ventricular (LV) function and AF detection.
  • To determine if echocardiography can guide AF monitoring strategies in TIA patients.

Main Methods:

  • 110 TIA patients without prior stroke or AF underwent echocardiography.
  • Patients were monitored using ECG, 72-hour Holter, and implantable cardiac monitors (ICM).
  • Echocardiographic parameters including LA volume, LA emptying fraction, LV ejection fraction, and LV global longitudinal strain were analyzed.

Main Results:

  • AF was detected in 14 patients (12.7%) during follow-up.
  • Patients with AF showed significantly larger LA volumes (2D and 3D) and depressed LA function (LA emptying fraction).
  • AF patients also exhibited depressed LV function, including lower LV ejection fraction and reduced LV global longitudinal strain.

Conclusions:

  • Echocardiographic assessment of LA and LV size and function can noninvasively predict AF in TIA patients.
  • These findings suggest echocardiography may help identify TIA patients at higher risk for AF.
  • Echocardiographic data could potentially guide the intensity and duration of AF monitoring in TIA patients.

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