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Toward a framework for best practices and research guidelines for perinatal depression research
Mary C Kimmel1, Anna Bauer1, Samantha Meltzer-Brody1
1Department of Psychiatry, School of Medicine, University of North Carolina, Chapel Hill, North Carolina.
Perinatal depression (PND) research needs better tools and standardized measures for identification, prevention, and treatment. Future precision in perinatal psychiatry requires collaborative guidelines and best practices.
Area of Science:
- Perinatal Psychiatry
- Reproductive Mental Health
- Translational Research
Background:
- Perinatal depression (PND) significantly impacts mothers, infants, and families.
- Current identification, prevention, and treatment strategies for PND remain limited.
- PND is a heterogeneous condition with multifactorial etiologies.
Purpose of the Study:
- To review the current state of perinatal depression research.
- To discuss challenges and opportunities in PND research and treatment.
- To outline recommendations for future PND research and collaboration.
Main Methods:
- Review of epidemiologic studies in PND research.
- Examination of biological underpinnings of PND.
- Discussion of translational research approaches from bench to bedside.
- Analysis of the NIMH Research Domain Criteria approach.
Main Results:
- Significant challenges exist in PND research, including the need for universal tools, standardized measures, and best practices.
- Innovative treatment paradigms and interventions are being developed.
- Translational research is advancing understanding and treatment of PND.
Conclusions:
- Greater precision in perinatal psychiatry is achievable through collaborative development of guidelines and best practices.
- Future directions emphasize innovative and collaborative approaches involving diverse stakeholders.
- Standardized measures and best practices are crucial for improving PND care.
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