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Updated: Jan 27, 2026

Inducement and Evaluation of a Murine Model of Experimental Myopia
Published on: January 22, 2019
Imaging of Pathologic Myopia
Kyoko Ohno-Matsui1, Yuxin Fang, Kosei Shinohara
1From the Department of Ophthalmology and Visual Science, Tokyo Medical and Dental University, Tokyo, Japan.
Abstract:
Pathologic myopia (PM) is a major cause of irreversible visual impairment worldwide and especially in East Asian countries. The complications of PM include myopic maculopathy, myopic macular retinoschisis, dome-shaped macula, and myopic optic neuropathy. Posterior staphyloma is an important component of the diagnosis of PM and one of the hallmarks of PM. The photographic classification and grading system for myopic maculopathy has already been determined. Conventionally optical coherence tomography (OCT) was commonly used in PM and enabled investigators to image deeper tissue such as choroid and sclera. Today, the technological advances in OCT imaging including ultra-widefield OCT and 3-dimensional construction of OCT have given clinicians a novel insight on variable morphology in the PM.
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