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Related Experiment Video

Updated: Jan 27, 2026

Inducement and Evaluation of a Murine Model of Experimental Myopia

Inducement and Evaluation of a Murine Model of Experimental Myopia

Published on: January 22, 2019

Imaging of Pathologic Myopia.

Kyoko Ohno-Matsui¹, Yuxin Fang, Kosei Shinohara

¹From the Department of Ophthalmology and Visual Science, Tokyo Medical and Dental University, Tokyo, Japan.

Asia-Pacific Journal of Ophthalmology (Philadelphia, Pa.)

|March 30, 2019

Summary

This summary is machine-generated.

Pathologic myopia (PM) causes irreversible vision loss globally. Advanced optical coherence tomography (OCT) imaging reveals new insights into the varied structures of the eye affected by PM.

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Area of Science:

Ophthalmology
Medical Imaging

Background:

Pathologic myopia (PM) is a leading cause of irreversible visual impairment worldwide, particularly in East Asia.
Key complications include myopic maculopathy, macular retinoschisis, dome-shaped macula, and optic neuropathy.
Posterior staphyloma is a diagnostic hallmark of PM.

Purpose of the Study:

To explore the utility of advanced optical coherence tomography (OCT) imaging in understanding the complex morphology of pathologic myopia.
To highlight novel insights provided by ultra-widefield OCT and 3D OCT constructions in PM assessment.

Main Methods:

Utilized advanced optical coherence tomography (OCT) imaging techniques.
Incorporated ultra-widefield OCT and 3-dimensional OCT construction.
Analyzed variable morphology associated with pathologic myopia.

Main Results:

Technological advancements in OCT provide unprecedented visualization of deeper ocular tissues like the choroid and sclera.
Ultra-widefield and 3D OCT offer novel perspectives on the diverse structural changes in PM.
These imaging modalities enhance the understanding of PM's intricate features.

Conclusions:

Advanced OCT imaging, including ultra-widefield and 3D techniques, offers significant advantages in visualizing and understanding the complex morphology of pathologic myopia.
These technologies provide clinicians with novel insights into the variable structures affected by PM, aiding diagnosis and research.