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Updated: Jan 27, 2026

Structured Motor Rehabilitation After Selective Nerve Transfers
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Supercharge End-to-Side Nerve Transfer: Systematic Review.

John C Dunn1, Gilberto A Gonzalez2, Isaac Fernandez2

  • 1William Beaumont Army Medical Center, El Paso, TX, USA.

Hand (New York, N.Y.)
|March 30, 2019
PubMed
Summary

Supercharged end-to-side (SETS) nerve transfer effectively restores intrinsic hand function after ulnar nerve injuries. This procedure shows high success rates and low complication rates, improving grip and pinch strength.

Keywords:
SETSsupercharged end-to-side transferulnar nerve

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Area of Science:

  • Neurosurgery
  • Orthopedic Surgery
  • Hand Surgery

Background:

  • High ulnar nerve injuries can impair intrinsic motor end plate reinnervation.
  • The supercharged end-to-side (SETS) anterior interosseous to ulnar motor nerve transfer is a proposed solution.
  • This review examines the clinical application of the SETS procedure.

Purpose of the Study:

  • To review indications for SETS nerve transfer.
  • To analyze outcomes of SETS nerve transfer.
  • To report complications associated with SETS nerve transfer.

Main Methods:

  • Literature search conducted for studies from 2000-2018.
  • Inclusion criteria identified 4 relevant studies.
  • Data from 78 patients were pooled and analyzed.

Main Results:

  • Most patients had ulnar nerve lesions in continuity; average age was 46.5 years.
  • Significant improvements in grip (202%) and key pinch strength (179%) were observed.
  • 91.9% of patients recovered intrinsic function with minimal complications (8% did not recover strength).

Conclusions:

  • SETS nerve transfer is a successful procedure for ulnar nerve injuries.
  • The technique demonstrates low morbidity and effective restoration of intrinsic function.
  • It offers a viable option for patients with proximal nerve injuries.