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Updated: Jan 27, 2026

Identifying Protein-protein Interaction Sites Using Peptide Arrays
Published on: November 18, 2014
Temperature-assisted formation of reversible metallophilic Au-Ag interaction arrays
María Gil-Moles1, M Concepción Gimeno, José M López-de-Luzuriaga
1Departamento de Química, Universidad de La Rioja, Centro de Investigación en Síntesis Química (CISQ), Complejo Científico-Tecnológico, 26004-Logroño, Spain. josemaria.lopez@unirioja.es.
Abstract:
A temperature-controlled self-assembly process in a solution of [Ag(terpy)]nn+ and [Au(C6F5)2]- units has been performed. For this, the crystallisation of the complex [{Au(C6F5)2}Ag(terpy)]n under the same experimental conditions, changing only the temperature, allows the synthesis of polymorphs [{Au(C6F5)2}2Ag2(terpy)2]n (2a) at 298 K and [{Au(C6F5)2}Ag(terpy)]n (2b) at 280 K. The X-ray diffraction studies previously reported for 2a revealed a polymeric structure with an unusual + + - - + + - - charge sequence, whereas for polymorph 2b, a more classical + - + - disposition has been obtained. The conversion of one polymorph into the other can be achieved by simple dissolution of one of them and by recrystallisation at the corresponding temperature. The mechanism of the formation of each polymorph is proposed in view of their 1H NMR, 1H-PGSE NMR and molar conductivity measurements.
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