Related Experiment Video

Updated: Jan 27, 2026

Studying Brain Function in Children Using Magnetoencephalography
08:00

Studying Brain Function in Children Using Magnetoencephalography

Published on: April 8, 2019

9.6K

Perioperative fluid management in children: can we sum it all up now?

Robert Sümpelmann1, Karin Becke2, Rolf Zander3

  • 1Clinic of Anaesthesiology, Hannover Medical School, Hannover.

Current Opinion in Anaesthesiology
|March 30, 2019
PubMed

Insights

Balanced isotonic electrolyte solutions are recommended for pediatric anesthesia fluid management. These solutions enhance patient safety and metabolic stability during surgery, improving outcomes.

Area of Science:

  • Pediatric Anesthesia
  • Intravenous Fluid Therapy
  • Perioperative Care

Background:

  • Perioperative fluid management in children is complex and critical for preventing adverse outcomes.
  • Historical debates surround intravenous fluid composition and type during pediatric anesthesia.

Purpose of the Study:

  • To review historical and current recommendations for pediatric perioperative fluid management.
  • To focus on physiological principles for safe and effective fluid administration in children.

Main Methods:

  • Review of historical and recent literature on pediatric fluid management.
  • Analysis of physiological data related to fluid balance and electrolyte composition.

Main Results:

  • Optimized fasting and clear fluid intake improve patient comfort and hemodynamics.
  • Balanced isotonic electrolyte solutions are safer than hypotonic or 0.9% saline solutions.
  • Intraoperative glucose infusion prevents hypoglycemia; colloids can manage circulatory instability.

Conclusions:

  • Physiologically balanced isotonic electrolyte solutions are beneficial for homeostasis in pediatric patients.
  • These solutions offer a wide safety margin, even with accidental hyperinfusion.
  • They help normalize patient status, particularly those with pre-existing imbalances.
Abstract

More Related Videos

A Mouse Tumor Model of Surgical Stress to Explore the Mechanisms of Postoperative Immunosuppression and Evaluate Novel Perioperative Immunotherapies13:37

A Mouse Tumor Model of Surgical Stress to Explore the Mechanisms of Postoperative Immunosuppression and Evaluate Novel Perioperative Immunotherapies

Published on: March 12, 2014

30.5K
Quantitative Assessment of Cortical Auditory-tactile Processing in Children with Disabilities09:38

Quantitative Assessment of Cortical Auditory-tactile Processing in Children with Disabilities

Published on: January 29, 2014

11.3K

Related Concept Videos

Sums of Power01:22

Sums of Power

In definite integration, Riemann sums approximate the area under a curve by dividing it into subintervals and summing the areas of rectangles. When these approximations follow predictable numerical patterns, such as arithmetic or polynomial sequences, sum formulas offer a more efficient and accurate way to compute the result. In particular, the sum of consecutive integers, squares, and cubes plays an essential role in simplifying these calculations, especially when dealing with uniform...
65
Wilcoxon Rank-Sum Test01:21

Wilcoxon Rank-Sum Test

The Wilcoxon rank-sum test, also known as the Mann-Whitney U test, is a nonparametric test used to determine if there is a significant difference between the distributions of two independent samples. This test is designed specifically for two independent populations and has the following key requirements:
736
Sum and Difference OpAmps01:22

Sum and Difference OpAmps

Operational amplifiers (op-amps) are versatile devices that extend beyond amplification. In this context, two specific op-amp configurations are explored: the summing and difference amplifiers.
A summing amplifier, or an adder, utilizes an op-amp to merge multiple input signals into a single output signal. When audio signals are introduced into its input channels, the input resistors initiate currents that traverse feedback resistors, resulting in an output voltage. Applying Kirchhoff's current...
1.4K
The Fluid Mosaic Model01:34

The Fluid Mosaic Model

The fluid mosaic model was first proposed as a visual representation of research observations. The model comprises the composition and dynamics of membranes and serves as a foundation for future membrane-related studies. The model depicts the structure of the plasma membrane with a variety of components, which include phospholipids, proteins, and carbohydrates. These integral molecules are loosely bound, defining the cell’s border and providing fluidity for optimal function.
177.6K
Accelerating Fluids01:17

Accelerating Fluids

When a fluid is in constant acceleration, the pressure and buoyant force equations are modified. Suppose a beaker is placed in an elevator accelerating upward with a constant acceleration, a. In the beaker, assume there is a thin cylinder of height h with an infinitesimal cross-sectional area, ΔS.
The motion of the liquid within this infinitesimal cylinder is considered to obtain the pressure difference. Three vertical forces act on this liquid:
2.3K
Cerebrospinal Fluid01:21

Cerebrospinal Fluid

Cerebrospinal fluid (CSF) is a colorless liquid that flows around the brain and the spinal cord, playing a vital role in the protection, support, and overall function of the central nervous system (CNS). CSF production, circulation, and absorption are tightly regulated processes essential for the brain and spinal cord to function properly.
CSF Production
CSF is produced mainly in the choroid plexus, a network of capillaries and ependymal cells located within the ventricular system of the brain....
5.6K