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Maturational Changes in Human Dorsal and Ventral Visual Networks
Kristina T R Ciesielski1,2, Moriah E Stern2, Adele Diamond3
1Department of Radiology, MGH/MIT/HMS A. A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Charlestown MA 02129, USA.
Cerebral Cortex (New York, N.Y. : 1991)
|March 31, 2019
Summary
The dorsal visual network (DVN) matures earlier than the ventral visual network (VVN) in typically developing children, influencing cognitive development. This finding supports an earlier maturation of the DVN in the neuro-cognitive trajectory.
Area of Science:
- Neuroscience
- Developmental Biology
- Cognitive Science
Background:
- Cognitive functions develop alongside changes in brain structure, including cortical thickness and connectivity.
- Synapse elimination is a key process in experience-dependent brain maturation.
Purpose of the Study:
- To determine which visual processing network, dorsal (DVN) or ventral (VVN), matures earlier in typically developing individuals.
- To investigate the developmental trajectory of neuro-cognitive maturation.
Main Methods:
- Structural T1-weighted MRI was used to assess cortical thickness (CTh) and structural connectivity in DVN and VVN.
- Neuropsychological tests evaluated proficiency in network-related cognitive functions.
- Participants included children (~6 years), adolescents (~11 years), and adults (~21 years).
Main Results:
- The dorsal visual network (DVN) showed no significant group differences in CTh or connectivity, except for the left prefrontal cortex.
- The ventral visual network (VVN) exhibited thicker cortex in children, with reduced prefrontal-ventral connectivity and abundant connections in adolescents.
- Children performed better on DVN-related tests, aligning with structural connectivity findings.
Conclusions:
- The dorsal visual network (DVN) demonstrates an earlier maturational course compared to the ventral visual network (VVN).
- This earlier maturation of the DVN may lead the overall neuro-cognitive developmental trajectory.
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