Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Structure-Activity Relationships and Drug Design01:28

Structure-Activity Relationships and Drug Design

1.7K
Drug design is a dynamic field that involves discovering and developing new medications based on specific biological targets. This process heavily relies on structure-activity relationships (SAR) and quantitative structure-activity relationships (QSAR) to guide the design and optimization of efficient drugs.
SAR studies the intricate relationship between a drug's chemical structure and biological activity. It focuses on understanding how modifications to a drug's structure can influence...
1.7K
Cholinergic Antagonists: Chemistry and Structure-Activity Relationship01:29

Cholinergic Antagonists: Chemistry and Structure-Activity Relationship

2.7K
Cholinergic antagonists bind to cholinergic receptors and limit the effects of acetylcholine and other cholinergic agonists. Based on the specific cholinergic receptor affinity, these antagonists are classified as muscarinic or nicotinic. Anticholinergics interrupt parasympathetic innervations while sympathetic innervations remain uninterrupted. Muscarinic antagonists are also called 'muscarinic antagonists', 'antimuscarinics', or 'parasympatholytics'. Nicotinic...
2.7K
Adrenergic Agonists: Chemistry and Structure-Activity Relationship01:16

Adrenergic Agonists: Chemistry and Structure-Activity Relationship

3.9K
Adrenergic agonists' structure-activity relationship (SAR) determines their selectivity and efficacy. These agonists comprise a phenylethylamine moiety with an aromatic ring and an ethylamine side chain.
Aromatic ring substitutions: Substituting the aromatic ring with –OH groups at positions 3 and 4 yields catecholamines (e.g., epinephrine), which have a high affinity for adrenoceptors. Hydrogen bonding between –OH groups and receptors enhances adrenergic activity.
Separation of...
3.9K
Local Anesthetics: Chemistry and Structure-Activity Relationship01:30

Local Anesthetics: Chemistry and Structure-Activity Relationship

6.5K
Local anesthetics (LAs) are drugs that induce a temporary loss of sensation in a limited body area, preventing pain. Cocaine was the first local anesthetic discovered in the late 19th century. Cocaine is a benzoic acid ester obtained from the leaves of coca shrubs and was often used for its psychotropic effects. Cocaine was first isolated in 1860 by Albert Niemann. Sigmund Freud studied the physiological actions of cocaine. Carl Koller later introduced it into clinical practice in 1884 as a...
6.5K
Direct-Acting Cholinergic Agonists: Chemistry and Structure-Activity Relationship01:22

Direct-Acting Cholinergic Agonists: Chemistry and Structure-Activity Relationship

2.1K
Cholinergic agonists or cholinomimetics mimic the action of acetylcholine to stimulate the parasympathetic nervous system. They are categorized into direct-acting and indirect-acting agents. The direct-acting cholinergic drugs induce the parasympathetic response by directly binding to the muscarinic or nicotine receptors. In comparison, the indirect-acting cholinergic drugs prevent acetylcholine hydrolysis, indirectly contributing to the extended parasympathetic response.
The direct-acting...
2.1K
Indirect-Acting Cholinergic Agonists: Chemistry and Structure-Activity Relationship01:29

Indirect-Acting Cholinergic Agonists: Chemistry and Structure-Activity Relationship

942
Indirect-acting cholinergic agonists are agents that interact with the acetylcholinesterase enzyme in the synaptic cleft, preventing the breakdown of acetylcholine into choline and acetate. Consequently, the concentration of acetylcholine in the synaptic cleft increases. These agonists can be classified into reversible and irreversible inhibitors based on their duration of action.
Reversible inhibitors display short to medium durations of action. Short-acting agents include simple alcohols with...
942

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Misunderstandings in robotic surgical instruction: An exploratory discourse analysis.

American journal of surgery·2025
Same author

Ambiguity in robotic surgical instruction: lessons from remote and in-person simulation.

Advances in health sciences education : theory and practice·2025
Same author

Digital technology in medical visits: a critical review of its impact on doctor-patient communication.

Frontiers in psychiatry·2023
Same author

Navigating Intercultural Medical Encounters: An Examination of Patient-Centered Communication Practices with Italian and Foreign Cancer Patients Living in Italy.

Cancers·2023
Same author

Toward Neurodiversity: How Conversation Analysis Can Contribute to a New Approach to Social Communication Assessment.

Language, speech, and hearing services in schools·2022
Same author

Editorial: Qualitative Methods for Studying Groups.

Frontiers in psychology·2022

Related Experiment Video

Updated: Jan 27, 2026

Multispectral Real-time Fluorescence Imaging for Intraoperative Detection of the Sentinel Lymph Node in Gynecologic Oncology
06:37

Multispectral Real-time Fluorescence Imaging for Intraoperative Detection of the Sentinel Lymph Node in Gynecologic Oncology

Published on: October 20, 2010

23.8K

Structuring times and activities in the oncology visit.

Laura Sterponi1, Cristina Zucchermaglio2, Marilena Fatigante2

  • 1University of California, Berkeley, Institute of Human Development and Graduate School of Education, 2121 Berkeley Way, Berkeley, CA, 94720, USA.

Social Science & Medicine (1982)
|March 31, 2019
PubMed
Summary

This study explores how doctors and patients coordinate medical visits, focusing on managing time and tasks. Key findings highlight the use of textual artifacts and metapragmatic utterances for achieving mutual understanding and smooth interaction during oncology visits.

Keywords:
Conversation analysisDoctor-patient interactionEthnomethodologyItalyMetapragmatic utterancesOncologyTemporalityTextual artifacts

More Related Videos

Measuring Biophysical and Psychological Stress Levels Following Visitation to Three Locations with Differing Levels of Nature
05:33

Measuring Biophysical and Psychological Stress Levels Following Visitation to Three Locations with Differing Levels of Nature

Published on: June 19, 2019

8.9K
Generation of Comprehensive Thoracic Oncology Database - Tool for Translational Research
11:18

Generation of Comprehensive Thoracic Oncology Database - Tool for Translational Research

Published on: January 22, 2011

16.5K

Related Experiment Videos

Last Updated: Jan 27, 2026

Multispectral Real-time Fluorescence Imaging for Intraoperative Detection of the Sentinel Lymph Node in Gynecologic Oncology
06:37

Multispectral Real-time Fluorescence Imaging for Intraoperative Detection of the Sentinel Lymph Node in Gynecologic Oncology

Published on: October 20, 2010

23.8K
Measuring Biophysical and Psychological Stress Levels Following Visitation to Three Locations with Differing Levels of Nature
05:33

Measuring Biophysical and Psychological Stress Levels Following Visitation to Three Locations with Differing Levels of Nature

Published on: June 19, 2019

8.9K
Generation of Comprehensive Thoracic Oncology Database - Tool for Translational Research
11:18

Generation of Comprehensive Thoracic Oncology Database - Tool for Translational Research

Published on: January 22, 2011

16.5K

Area of Science:

  • Medical Sociology
  • Conversation Analysis
  • Health Communication

Background:

  • Medical visits require complex coordination between doctors and patients.
  • Managing time and tasks during appointments is challenging due to differing knowledge and dynamic needs.
  • Oncological visits present unique coordination challenges.

Purpose of the Study:

  • To examine the interactional coordination between doctors and patients during medical visits.
  • To identify the semiotic resources used for managing time and tasks in clinical encounters.
  • To analyze how mutual understanding and coordinated actions are achieved in oncology visits.

Main Methods:

  • Ethnographic study of oncological visits.
  • Conversation analytic approach to examine doctor-patient interactions.
  • Analysis of semiotic resources, including textual artifacts and metapragmatic utterances.

Main Results:

  • Doctor-patient coordination relies on managing time and praxis (task apportionment).
  • Challenges in coordination stem from unequal familiarity with tasks, dynamic attention needs, and limited visit time.
  • Textual artifacts and metapragmatic utterances are crucial for coordinating temporal trajectories and actions.

Conclusions:

  • Effective medical visit accomplishment depends on sophisticated interactional coordination.
  • Semiotic resources play a vital role in navigating the complexities of clinical encounters.
  • Understanding these coordination mechanisms can improve healthcare communication and patient experience in oncology.