Related Experiment Video
Updated: Jan 27, 2026
Cardiopulmonary Bypass in a Mouse Model: A Novel Approach
Published on: September 22, 2017
What's New in Cardiopulmonary Bypass
1Department of Anesthesiology, College of Medicine, University of Kentucky, Lexington, KY.
Insights
This review covers recent advancements in cardiopulmonary bypass (CPB) for cardiac anesthesiologists, focusing on temperature, anticoagulation, and perfusion practices. It highlights key developments impacting anesthesia care during cardiac surgery.
Area of Science:
- Cardiovascular Anesthesiology
- Cardiopulmonary Bypass (CPB) Management
Background:
- Cardiac surgery often requires cardiopulmonary bypass (CPB), a complex procedure with evolving best practices.
- Anesthesiologists play a critical role in managing patients undergoing CPB.
Purpose of the Study:
- To provide a narrative review of recent literature (2017-2018) relevant to CPB conduct.
- To inform cardiac anesthesiologists about current trends and guidelines in CPB management.
Main Methods:
- Literature review of articles published primarily in 2017 and 2018.
- Focus on topics pertinent to the practice of cardiac anesthesia during CPB.
Main Results:
- Recent guidelines and practices in temperature management, anticoagulation, and perfusion.
- Updates on managing vasoplegia, bleeding, perioperative anemia, and transfusion strategies.
- Insights into acute kidney injury, delirium, cognitive decline, and CPB in pregnancy.
- Discussions on lung management, pressure gradients, perioperative interventions, cardioplegia, and antibiotic prophylaxis.
- Evaluation of levosimendan use and its impact on cardiac surgery outcomes.
Conclusions:
- The review synthesizes recent developments impacting the practice of cardiac anesthesia.
- It offers a perspective on how these advancements shape perioperative care during CPB.
Abstract:
This is a narrative review of recent articles (mainly published in 2017 and 2018) related to the conduct of cardiopulmonary bypass (CPB) that should be of interest to the cardiac anesthesiologist. Some of the topics covered include recent guidelines on temperature management, anticoagulation, perfusion practice, use of transesophageal echocardiography during CPB, optimal mean arterial pressure, vasoplegia, bleeding, perioperative anemia, post-cardiac surgery transfusion, acute kidney injury, delirium and cognitive decline, CPB during pregnancy, lung management, radial-to-femoral artery pressure gradients during CPB, prophylactic perioperative intra-aortic balloon pump, del Nido cardioplegia, antibiotic prophylaxis, and use of levosimendan in cardiac surgery. The review concludes with a perspective on the effect of these development on the practice of cardiac anesthesia.
