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Cardiopulmonary Bypass in a Mouse Model: A Novel Approach
Published on: September 22, 2017
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What's New in Cardiopulmonary Bypass
1Department of Anesthesiology, College of Medicine, University of Kentucky, Lexington, KY.
Journal of Cardiothoracic and Vascular Anesthesia
|April 1, 2019
Summary
This review covers recent advancements in cardiopulmonary bypass (CPB) for cardiac anesthesiologists, focusing on temperature, anticoagulation, and perfusion practices. It highlights key developments impacting anesthesia care during cardiac surgery.
Area of Science:
- Cardiovascular Anesthesiology
- Cardiopulmonary Bypass (CPB) Management
Background:
- Cardiac surgery often requires cardiopulmonary bypass (CPB), a complex procedure with evolving best practices.
- Anesthesiologists play a critical role in managing patients undergoing CPB.
Purpose of the Study:
- To provide a narrative review of recent literature (2017-2018) relevant to CPB conduct.
- To inform cardiac anesthesiologists about current trends and guidelines in CPB management.
Main Methods:
- Literature review of articles published primarily in 2017 and 2018.
- Focus on topics pertinent to the practice of cardiac anesthesia during CPB.
Main Results:
- Recent guidelines and practices in temperature management, anticoagulation, and perfusion.
- Updates on managing vasoplegia, bleeding, perioperative anemia, and transfusion strategies.
- Insights into acute kidney injury, delirium, cognitive decline, and CPB in pregnancy.
- Discussions on lung management, pressure gradients, perioperative interventions, cardioplegia, and antibiotic prophylaxis.
- Evaluation of levosimendan use and its impact on cardiac surgery outcomes.
Conclusions:
- The review synthesizes recent developments impacting the practice of cardiac anesthesia.
- It offers a perspective on how these advancements shape perioperative care during CPB.

