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A Case of Cerebral Venous Sinus Thrombosis Presenting During Relapse of Ulcerative Colitis

Abubaker O Abdalla1, Deepti Alluri1, Mohamed Hassaballa1

  • 1Department of Internal Medicine, University of Nevada, School of Medicine, Reno, NV, USA.

The American Journal of Case Reports
|April 1, 2019
PubMed

Insights

Inflammatory bowel disease (IBD) can cause rare but serious blood clots in the brain, known as cerebral venous sinus thrombosis. Early recognition and treatment are crucial for patients with IBD experiencing neurological symptoms.

Area of Science:

  • Neurology
  • Gastroenterology
  • Hematology

Background:

  • Extra-intestinal manifestations of inflammatory bowel disease (IBD) include thromboembolic events.
  • Cerebral venous sinus thrombosis (CVST) is a rare but serious complication of IBD.

Observation:

  • A 27-year-old male with a history of ulcerative colitis (UC) presented with seizures and focal neurological deficits during a disease relapse.
  • The patient was diagnosed with left CVST complicated by left frontotemporal infarction.

Findings:

  • CVST can be a presenting or complicating feature in patients with IBD, particularly during active disease.
  • Anticoagulation therapy was initiated for the CVST and infarction.

Implications:

  • This case highlights the importance of considering CVST in IBD patients with new-onset neurological symptoms.
  • Timely diagnosis and management of CVST are critical to reduce morbidity and mortality in IBD patients.

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