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Updated: Jan 27, 2026

Electroretinogram Recording for Infants and Children under Anesthesia to Achieve Optimal Dark Adaptation and International Standards
Published on: September 3, 2020
ISCEV extended protocol for the stimulus-response series for the dark-adapted full-field ERG b-wave
Mary A Johnson1, Brett G Jeffrey2, André M V Messias3
1Department of Ophthalmology and Visual Sciences, University of Maryland School of Medicine, 10 S. Pine St., MSTF Suite 500-A, Baltimore, MD, 21201, USA. maryjohnson@som.umaryland.edu.
None:
The International Society for Clinical Electrophysiology of Vision (ISCEV) standard for full-field electroretinography (ERG) describes a minimum protocol for clinical testing but encourages more extensive testing where appropriate. This ISCEV extended protocol describes an extension of the ISCEV full-field ERG standard, in which methods to record and evaluate the growth of the dark-adapted (DA) ERG b-wave with increasing stimulus energy are described. The flashes span a range that includes the weakest flash required to generate a reliable DA ERG b-wave and that required to generate a maximal b-wave amplitude. The DA ERG b-wave stimulus-response series (also known historically as the "intensity-response" or "luminance-response" series) can more comprehensively characterize generalized rod system function than the ISCEV standard ERG protocol and may be of diagnostic or prognostic value in disorders that cause generalized rod system dysfunction.
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