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Clinical significance and sonographic evolution of enlarged abdominal lymph nodes in children

Paolo Quitadamo1,2, Eleonora Giannetti1, Marialuisa Andreozzi1

  • 1Department of Translational Medical Science, Section of Pediatrics, "Federico II" University of Naples, Naples, Italy.

Acta Paediatrica (Oslo, Norway : 1992)
|April 1, 2019
PubMed

Insights

Enlarged abdominal lymph nodes (EALN) in children with recurrent abdominal pain are a non-specific finding. These nodes do not typically require changes in diagnostic or therapeutic management.

Area of Science:

  • Pediatric Gastroenterology
  • Pediatric Radiology

Background:

  • Clinical evidence regarding enlarged abdominal lymph nodes (EALN) in children with recurrent abdominal pain is inconsistent.
  • Understanding the clinical significance and evolution of EALN is crucial for appropriate patient management.

Purpose of the Study:

  • To evaluate the clinical significance of enlarged abdominal lymph nodes (EALN) in children experiencing recurrent abdominal pain.
  • To assess the morphological evolution of EALN over a six-month period in this pediatric cohort.

Main Methods:

  • Children diagnosed with EALN and recurrent abdominal pain were enrolled between September 2017 and June 2018.
  • Detailed recording of node characteristics (number, size, location, shape, architecture) and clinical/laboratory data at baseline and follow-up (3 and 6 months).

Main Results:

  • Out of 38 enrolled children, 58% showed reduced lymph node size, 13% had unchanged nodes, and 29% had increased node size after six months.
  • A slight, gradual reduction in average enlarged node size was observed over the study period.
  • No correlation was found between the extent of size changes and any clinical parameter.

Conclusions:

  • Enlarged abdominal lymph nodes (EALN) in children with recurrent abdominal pain represent a non-specific finding.
  • EALN do not warrant alterations in the current diagnostic or therapeutic strategies for pediatric abdominal pain.
Abstract

Keywords:
AbdomenChildrenLymph nodeLymphadenitisUltrasonography

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