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Published on: November 27, 2019
Exact testing with random permutations
1Department of Medical Statistics and Bioinformatics, Leiden University Medical Center, Postzone S5-P, Postbus 9600, 2300 RC Leiden, The Netherlands.
Abstract:
When permutation methods are used in practice, often a limited number of random permutations are used to decrease the computational burden. However, most theoretical literature assumes that the whole permutation group is used, and methods based on random permutations tend to be seen as approximate. There exists a very limited amount of literature on exact testing with random permutations, and only recently a thorough proof of exactness was given. In this paper, we provide an alternative proof, viewing the test as a "conditional Monte Carlo test" as it has been called in the literature. We also provide extensions of the result. Importantly, our results can be used to prove properties of various multiple testing procedures based on random permutations.
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