From the Gut to the Heart: Cardiac Tamponade due to Lymphatic Metastasis

Malignant pericardial effusion is common, being reported in 5-15% of all cancer patients. It most commonly arises from metastasis of lymphomas and of tumours of the lung, breast and, infrequently, the gastrointestinal tract. We describe the case of a 76-year-old woman who presented to the emergency room with cervical adenopathies and clinical signs of acute heart failure. The nodes were biopsied and found to be consistent with adenocarcinoma of the colon. CT showed thoracic lymphatic involvement but no evidence of other organ involvement. The patient developed cardiac tamponade and required emergent pericardiocentesis. To our knowledge, this is the first report of metastatic colon cancer without direct involvement of the pericardium or other solid organs.

Large pericardial effusions are common in cancer patients.The pericardium in cancer patients may be affected by haematogenous or lymphatic spread or by local extension.A gastrointestinal origin of malignant pericardial effusions is rare but should be considered as a possible diagnosis.