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Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
Published on: January 18, 2018
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Microalbuminuria in patients with acute ischemic stroke
Fei Li1, Qian-Xue Chen1, Bo Peng2
1a Department of Neurosurgery , Renmin Hospital of Wuhan University , Wuhan , China.
Neurological Research
|April 2, 2019
Summary
Microalbuminuria, a marker found in about one-third of acute ischemic stroke patients, correlates with stroke severity and predicts poor outcomes. This finding highlights its potential as a prognostic indicator in cerebral infarction.
Area of Science:
- Neurology
- Nephrology
- Cardiovascular Medicine
Background:
- Microalbuminuria is detectable in acute stroke patients.
- The link between microalbuminuria and ischemic stroke severity requires systematic investigation.
Purpose of the Study:
- To determine the prevalence of microalbuminuria in ischemic stroke.
- To assess the association between microalbuminuria and stroke severity.
- To evaluate the prognostic value of microalbuminuria in cerebral infarction.
Main Methods:
- 160 ischemic stroke patients and 54 controls were analyzed.
- Stroke severity was measured using the NIHSS score; outcomes were assessed with the mRS score.
- Urinary microalbumin concentration was measured, and regression analyses were performed.
Main Results:
- 36.88% of ischemic stroke patients had microalbuminuria.
- Urinary microalbumin levels correlated with cerebral infarction size, NIHSS score, and 3-month mRS score.
- Microalbuminuria was an independent risk factor for poor prognosis in cerebral infarction.
Conclusions:
- Microalbuminuria affects approximately one-third of acute ischemic stroke patients.
- It correlates with stroke severity and 3-month clinical outcomes.
- Microalbuminuria may serve as a potential indicator of poor prognosis in ischemic stroke.
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