Related Experiment Video
Updated: Jan 27, 2026

Author Spotlight: Developing a Point-of-Care Hemoglobin Estimation Method for Anemia Management
Published on: January 19, 2024
Clinical Decision Support Tools and a Standardized Order Set Enhances Early Enteral Nutrition in Critically Ill
Keegan J Ziemba1,2, Rajeswari Kumar1, Kathryn Nuss1
1Nationwide Children's Hospital, Columbus, Ohio, USA.
Insights
Implementing an enteral nutrition (EN) algorithm in a pediatric intensive care unit (PICU) improved early nutrition delivery and reduced length of stay. This nutrition protocol enhanced patient outcomes for critically ill children.
Area of Science:
- Pediatric Intensive Care
- Clinical Nutrition
- Quality Improvement
Background:
- Critically ill children in the PICU face malnutrition due to complex nutrition needs.
- Early achievement of caloric goals is linked to better outcomes in pediatric patients.
- Current nutrition delivery methods in PICU settings are often suboptimal.
Purpose of the Study:
- To implement an enteral nutrition (EN) algorithm in a tertiary care PICU.
- To utilize clinical decision support tools (CDSTs) and standardized order sets for nutrition management.
- To improve the delivery of nutrition to critically ill children.
Main Methods:
- A quality improvement initiative was conducted.
- An EN feeding protocol was implemented using electronic CDSTs.
- A standardized order set was integrated into the electronic health record.
Main Results:
- Pre-implementation, only 18% of patients met goal EN within 48 hours.
- Post-implementation, 88% of patients achieved goal feed volume within 48 hours.
- Significant improvements were observed in time to start EN, time to goal nutrition, and reduced PICU length of stay.
Conclusions:
- CDSTs and standardized order sets effectively facilitated the implementation of a nutrition algorithm.
- The nutrition algorithm likely improved the nutrition care of critically ill children.
- This initiative demonstrates a successful strategy for optimizing EN delivery in the PICU.
Background:
Critically ill children in a pediatric intensive care unit (PICU) have unique nutrition needs that are challenging to achieve and thus are at high risk of malnutrition. There is increasing evidence that children who reach caloric goals early have improved outcomes. The purpose of this initiative was to implement an enteral nutrition (EN) algorithm in a tertiary care PICU utilizing clinical decision support tools (CDSTs) and a standardized order set within an electronic health record.
Methods:
A quality improvement initiative was undertaken to implement an EN feeding protocol using electronic CDSTs, including a new standardized order set.
Results:
In a historical cohort of 376 patients, only 18% met goal EN in the first 48 hours of admission. The EN protocol was implemented in 272 patients who met 88% goal feed volume within 48 hours of intensive care unit admission. Median time to start EN (1.7 vs 1.3 days, P < 0.0001) and time to goal nutrition (2.8 vs 2.2 days, P < 0.001) improved after project implementation. Length of stay in the PICU was significantly reduced following protocol implementation (202 hours pre-implementation vs 156 hours post implementation, P < 0.0001).
Conclusions:
We used CDSTs and standardized order sets to implement a nutrition algorithm to facilitate and likely improve the nutrition care of critically ill children.
Related Concept Videos
Enteral Nutrition I: Orogastric and Nasogastric Feeding
Orogastric (OG) and nasogastric (NG) feeding are two standard methods used for enteral nutrition. Enteral nutrition is often preferred over...
Enteral Nutrition II: Nasointestinal and Gastrostomy Feeding
Nasointestinal Feeding
Nasointestinal feeding involves placing a tube...
The Roles of Bacteria and Fungi in Plant Nutrition
Key Elements for Plant Nutrition
Parentral Nutrition: Centeral and Peripheral Parental Nutrition
PN can be administered through two primary routes:
1. Central Parenteral Nutrition (CPN):
CPN involves delivering a high concentration of nutrients through a large vein. This is typically achieved using a Peripherally Inserted Central Catheter (PICC) or,...
Microbial Nutrition

