Related Experiment Video
Updated: Jan 27, 2026
05:44
Using Saccadometry with Deep Brain Stimulation to Study Normal and Pathological Brain Function
Published on: July 14, 2016
7.9K
Cutaneous leiomyosarcoma: a clinical, dermoscopic, pathologic case study
V De Giorgi1, F Scarfì1, F Silvestri1
1Department of Dermatology, University of Florence, Florence 50100, Italy.
Experimental Oncology
|April 2, 2019
Summary
Cutaneous leiomyosarcoma, a rare skin cancer originating from smooth muscle, presents unique diagnostic challenges. This case highlights the clinical and dermoscopic features of a superficial leiomyosarcoma on the thigh.
Area of Science:
- Dermatology
- Oncology
- Pathology
Background:
- Cutaneous leiomyosarcoma is a rare malignant mesenchymal tumor arising from smooth muscle tissue.
- It is categorized into superficial and metastatic types, with superficial leiomyosarcomas accounting for 7-10% of all leiomyosarcomas.
- The etiology of cutaneous leiomyosarcoma remains largely unknown.
Observation:
- A case report of an 81-year-old woman with a slow-growing, tender, single nodule on her left thigh.
- The lesion was identified as a cutaneous leiomyosarcoma.
- Clinical and dermoscopic examinations were performed.
Findings:
- The study details the clinical presentation of a superficial leiomyosarcoma.
- Dermoscopic features of this rare skin cancer are described.
- The nodule was characterized as tender and slow-growing.
Implications:
- This case contributes to understanding the clinical and dermoscopic presentation of cutaneous leiomyosarcoma.
- Enhanced diagnostic accuracy for superficial leiomyosarcomas can be achieved through detailed clinical and dermoscopic analysis.
- Further research into the etiology and optimal management of cutaneous leiomyosarcoma is warranted.
Related Concept Videos
01:21Aneurysm II: Clinical Manifestations and Diagnostic Studies
334
Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...
334
01:30Hypertension III: Clinical Manifestations and Diagnostic Studies
491
Hypertension is asymptomatic and also referred to as the "silent killer" until it progresses to a severe stage or causes target organ disease. Patients may experience symptoms stemming from the strain on blood vessels and tissues in various organs or the heart's increased workload.Physical exams might show no abnormalities other than high blood pressure. Signs of vascular damage, when present, correspond to the organs supplied by the affected vessels, leading to target organ damage. For...
491
01:20Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies
332
The key difference between Superficial Vein Thrombosis (SVT) and Deep Vein Thrombosis (DVT) lies in their location and severity.Clinical ManifestationsSVT typically presents with localized pain, tenderness, and redness along the course of a superficial vein, often accompanied by a palpable, cord-like structure under the skin. This condition is usually less dangerous than DVT but can be uncomfortable and may lead to complications such as cellulitis or, rarely, a clot extension into the deep...
332
01:22Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies
542
The key clinical manifestations of Rheumatic heart disease (RHD) include several distinct cardiac symptoms.Carditis, a hallmark of acute rheumatic fever, involves inflammation of the heart's endocardium, myocardium, and pericardium. Chronic RHD often results from recurrent episodes of carditis. Its symptoms include the following:Murmurs are caused by valvular damage, especially to the mitral and aortic valves. Mitral stenosis or regurgitation is common, with characteristic heart murmurs...
542
01:28Peptic Ulcer Disease III: Clinical Manifestations and Diagnostic Studies
562
Peptic ulcer disease (PUD) presents with diverse symptoms depending on the location and severity of the ulcer. Clinical manifestations of peptic ulcer include dull pain and a burning sensation in the mid-epigastric region.
Few clinical manifestations differentiate gastric ulcers from duodenal ulcers. Distinctions in the location, timing, and pain relief are crucial for healthcare providers in differentiating between gastric and duodenal ulcers during clinical assessments.
Few clinical manifestations differentiate gastric ulcers from duodenal ulcers. Distinctions in the location, timing, and pain relief are crucial for healthcare providers in differentiating between gastric and duodenal ulcers during clinical assessments.
562
01:16Clinical Trials
10.2K
Clinical trials are prospective experimental studies conducted on humans to determine the safety and efficacy of treatments, drugs, diet methods, and medical devices. Using statistics in clinical trials enables researchers to derive reasonable and accurate conclusions from the collected data, allowing them to make wise decisions in uncertain situations. In medical research, statistical methods are crucial for preventing errors and bias.
There are four phases in a clinical trial. A phase one...
There are four phases in a clinical trial. A phase one...
10.2K