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Updated: Jan 27, 2026

An Organotypic High Throughput System for Characterization of Drug Sensitivity of Primary Multiple Myeloma Cells
Published on: July 15, 2015
Treatment of Multiple Myeloma: ASCO and CCO Joint Clinical Practice Guideline
Joseph Mikhael1,2, Nofisat Ismaila3, Matthew C Cheung4
11 City of Hope Cancer Center, Phoenix, AZ.
Purpose:
To provide evidence-based recommendations on the treatment of multiple myeloma to practicing physicians and others.
Methods:
ASCO and Cancer Care Ontario convened an Expert Panel of medical oncology, surgery, radiation oncology, and advocacy experts to conduct a literature search, which included systematic reviews, meta-analyses, randomized controlled trials, and some phase II studies published from 2005 through 2018. Outcomes of interest included survival, progression-free survival, response rate, and quality of life. Expert Panel members used available evidence and informal consensus to develop evidence-based guideline recommendations.
Results:
The literature search identified 124 relevant studies to inform the evidence base for this guideline.
Recommendations:
Evidence-based recommendations were developed for patients with multiple myeloma who are transplantation eligible and those who are ineligible and for patients with relapsed or refractory disease.
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