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Updated: Jan 27, 2026

Synthesis and Functionalization of 3D Nano-graphene Materials: Graphene Aerogels and Graphene Macro Assemblies
Published on: November 5, 2015
Graphene-ferrocene functionalized cyclodextrin composite with high electrochemical recognition capability for
Xiaohui Niu1, Zunli Mo1, Xing Yang1
1Research Center of Gansu Military and Civilian Integration Advanced Structural Materials, Key Laboratory of Eco-Environment-Related Polymer Materials, Ministry of Education of China, Key Laboratory of Polymer Materials of Gansu Province, College of Chemistry and Chemical Engineering, Northwest Normal University, Lanzhou 730070, China.
Abstract:
Graphene oxide (GO) modified with ferrocene (Fc) was successfully assembled via the π-π interaction (GO-Fc) and had the features of large surface area and high loading. Then, a novel composite was synthesized via β-cyclodextrin (β-CD) functionalized GO-Fc by combining the advantages of GO-Fc and β-CD. An efficient chiral electrochemical sensing interface was constructed by using the rGO-Fc-CD composite as the electrode modification for the recognition of phenylalanine (Phe) enantiomers. The successful synthesis of the composites was confirmed by FTIR, XRD, TGA, SEM, and XPS results. The host-guest inclusion interaction was detected by ultraviolet spectroscopy and DPV. The recognition results demonstrated that the rGO-Fc-CD/GCE showed a higher chiral recognition capability for L-Phe than for D-Phe. The enantioselectivity coefficient (ID/IL) of the proposed sensor was 2.47. The LOD values of 27 nM and 52 nM (S/N = 3) for L-Phenylalanine and D-Phenylalanine were obtained for this electrochemical sensor. The as-synthesized material was successfully exploited for the recognition of Phe enantiomers, indicating that the developed sensor has wide application prospects.
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