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Published on: July 27, 2021
Comparisons between ethnic groups in hospitalizations for respiratory syncytial virus bronchiolitis in Israel
Eias Kassem1, Wasef Na'amnih2, Amna Bdair-Amsha2
1Department of Pediatrics, Hillel Yaffe Medical Center, Hadera, Israel.
Insights
Ethnic disparities in respiratory syncytial virus (RSV) bronchiolitis hospitalizations were studied in Israel. Incidence was higher in Jewish children, but disease severity was not linked to ethnicity, with pneumonia being a key predictor.
Area of Science:
- Pediatrics
- Infectious Diseases
- Public Health
Background:
- Ethnic disparities in respiratory syncytial virus (RSV) bronchiolitis have been observed.
- The role of healthcare access in these disparities remains unclear.
- This study investigates ethnic differences in RSV bronchiolitis hospitalizations in Israel, a nation with universal healthcare.
Purpose of the Study:
- To compare demographic and clinical characteristics of Arab and Jewish children hospitalized for RSV bronchiolitis.
- To determine if ethnic differences in hospitalization rates are influenced by socioeconomic factors or healthcare access.
- To identify predictors of severe RSV bronchiolitis in a diverse pediatric population.
Main Methods:
- Retrospective review of medical records for 309 children under 24 months hospitalized with RSV between 2008-2011.
- Data collected included demographic, clinical, laboratory, and radiological information.
- RSV antigen identification was performed using immunochromatography.
Main Results:
- Annual RSV hospitalization incidence was 5.4/1000 for Arab children and 6.8/1000 for Jewish children.
- Arab patients were younger, had younger parents, and predominantly resided in low socioeconomic areas.
- Disease severity did not differ significantly between ethnic groups; pneumonia and prior respiratory disease history predicted severe illness.
Conclusions:
- RSV bronchiolitis hospitalization incidence may be higher in Jewish children, potentially due to healthcare utilization patterns.
- Observed demographic differences between Arab and Jewish children reflect general population disparities.
- Pneumonia, not ethnicity, was the primary determinant of RSV bronchiolitis severity.
Background:
Ethnic disparities have been shown in respiratory syncytial virus (RSV) bronchiolitis. However, it is unclear whether such differences are related to access to care. We compared demographic and clinical characteristics of Arab and Jewish children hospitalized for RSV bronchiolitis in Israel, a country with universal health insurance.
Methods:
We reviewed the medical records of all children (n = 309) aged less than 24 months who were hospitalized with RSV between 2008 and 2011 in one medical center in Israel. Demographic, clinical, laboratory and radiological data were collected. The RSV antigen was identified using immunochromatography.
Results:
The annual incidence of RSV hospitalization was 5.4/1000 and 6.8/1000 among Arab and Jewish children, respectively. Arab patients were significantly younger and had significantly younger parents; most lived in low socioeconomic status towns (93.7% vs. 13.3%; p<0.001) and had more siblings (median 2 vs. 1; p = 0.01) compared to Jewish patients. Disease severity did not differ between the two ethnic groups (p = 0.3). The main predictors of severe illness were having pneumonia (adjusted odds ratio [OR] 3.86; 95% confidence intervals [CI] 1.87-7.97) and history of respiratory diseases (adjusted OR 3.89; 95% CI 1.22-12.38).
Conclusions:
The incidence of hospitalizations for RSV bronchiolitis tended to be higher among Jewish than Arab children, possibly due to differences in health care utilization patterns. Differences between the Jewish and Arab patients in demographic factors likely mirror differences between the groups in the general population. Pneumonia, and not ethnicity, affected the severity of RSV bronchiolitis.
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