Related Experiment Video
Updated: Jan 27, 2026

High-throughput Identification of Synergistic Drug Combinations by the Overlap2 Method
Published on: May 21, 2018
Role of hubs in the synergistic spread of behavior
Yongjoo Baek1, Kihong Chung2, Meesoon Ha3
1DAMTP, Centre for Mathematical Sciences, University of Cambridge, Cambridge CB3 0WA, United Kingdom.
Abstract:
The spread of behavior in a society has two major features: the synergy of multiple spreaders and the dominance of hubs. While strong synergy is known to induce mixed-order transitions (MOTs) at percolation, the effects of hubs on the phenomena are yet to be clarified. By analytically solving the generalized epidemic process on random scale-free networks with the power-law degree distribution p_{k}∼k^{-α}, we clarify how the dominance of hubs in social networks affects the conditions for MOTs. Our results show that, for α<4, an abundance of hubs drive MOTs, even if a synergistic spreading event requires an arbitrarily large number of adjacent spreaders. In particular, for 2<α<3, we find that a global cascade is possible even when only synergistic spreading events are allowed. These transition properties are substantially different from those of cooperative contagions, which are another class of synergistic cascading processes exhibiting MOTs.
Related Concept Videos
Spreading of Chromatin Modifications
Writers
The writer...
What is Behavior?
Role of Septins
Cellular Functions of Septins
Recent studies have revealed the multifaceted roles of septins in various cellular processes such as cytokinesis, ciliogenesis, and neurogenesis. Septins act as scaffolds and...
The Role of Culture
Role of Hippocampus in Memory
Role-Based Identity

