Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Tonicity in Animals00:59

Tonicity in Animals

123.4K
The tonicity of a solution determines if a cell gains or loses water in that solution. The tonicity depends on the permeability of the cell membrane for different solutes and the concentration of nonpenetrating solutes in the solution within and outside of the cell. If a semipermeable membrane hinders the passage of some solutes but allows water to follow its concentration gradient, water moves from the side with low osmolarity (i.e., less solute) to the side with higher osmolarity (i.e.,...
123.4K
Tonicity in Animals01:16

Tonicity in Animals

5.2K
Tonicity describes the amount of solute in a solution. The measure of the tonicity of a solution, or the total amount of solutes dissolved in a specific amount of solution, is called its osmolarity. Three terms—hypotonic, isotonic, and hypertonic—are used to relate the osmolarity of a cell to the osmolarity of the extracellular fluid that contains the cells. In a hypotonic solution, such as tap water, the extracellular fluid has a lower concentration of solutes than the fluid inside...
5.2K
Animal Mitochondrial Genetics02:59

Animal Mitochondrial Genetics

9.0K
Among all the organelles in an animal cell, only mitochondria have their own independent genomes. Animal mitochondrial DNA is a double-stranded, closed-circular molecule with around 20,000 base pairs. Mitochondrial DNA is unique in that one of its two strands, the heavy, or H, -strand is guanine rich, whereas the complementary strand is cytosine rich and called the light, or L, -strand. Compared to nuclear DNA, mitochondrial DNA has a very low percentage of non-coding regions and is marked by...
9.0K
Typical Model Studies01:30

Typical Model Studies

626
Fluid mechanics model studies often utilize scaled-down systems to predict fluid behavior in full-scale environments, such as river flows, dam spillways, and structures interacting with open surfaces. Maintaining Froude number similarity in river models is crucial, as it replicates surface flow features like wave patterns and velocities.
626
Mouse Models of Cancer Study02:43

Mouse Models of Cancer Study

6.5K
Mice have long served as models for studying human biology and pathology because of their phylogenetic and physiological similarity with humans. They are also easy to maintain and breed in the laboratory, and hence, many inbred strains are now available for research. Studies on mice have contributed immeasurably to our understanding of cancer biology.
The development of transgenic, knockout, and knock-in mice has led to an exponential increase in their use as model organisms in research,...
6.5K
Animal and Plant Cell Structure01:30

Animal and Plant Cell Structure

47.7K
Animal and plant cells not only differ in their structure, function, and mode of nutrition but also in how they reproduce, specialize, and organize into complex structures.
Cell Division
Though both plant and animal cells divide by mitosis (for non-gametic cells) and meiosis (for gametic cells), they differ in the specifics of this process. Unlike animal cells, plant cells lack centrosomes — an organelle responsible for organizing the spindle fibers and segregating the chromosomes during...
47.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Expression of Human CEACAM Receptors Promotes Inflammation and Organ Damage During Systemic <i>Candida albicans</i> Infection in Mice.

Cells·2026
Same author

Spatial proteomics for the analysis of host-pathogen interactions in mice lungs infected with <i>Aspergillus fumigatus</i>.

microLife·2026
Same author

Synergistic interactions between <i>Candida albicans</i> and <i>Enterococcus faecalis</i> promote toxin-dependent host cell damage.

Proceedings of the National Academy of Sciences of the United States of America·2025
Same author

A droplet microfluidic strategy for cultivation, investigation, and high-throughput isolation of mouse gut microbiome bacteria.

Applied and environmental microbiology·2025
Same author

Identification of a fungal antibacterial endopeptidase that cleaves peptidoglycan.

EMBO reports·2025
Same author

Synergistic cross-kingdom host cell damage between <i>Candida albicans</i> and <i>Enterococcus faecalis</i>.

bioRxiv : the preprint server for biology·2024

Related Experiment Video

Updated: Jan 27, 2026

Computer-Generated Animal Model Stimuli
26:43

Computer-Generated Animal Model Stimuli

Published on: July 29, 2007

11.3K

Animal Models to Study Mucormycosis.

Ilse D Jacobsen1,2

  • 1Research Group Microbial Immunology, Leibniz Institute for Natural Product Research and Infection Biology (Hans Knöll Institute), Beutenbergstrasse 11a, 07745 Jena, Germany. ilse.jacobsen@leibniz-hki.de.

Journal of Fungi (Basel, Switzerland)
|April 3, 2019
PubMed
Summary
This summary is machine-generated.

Animal models are vital for understanding mucormycosis, a severe fungal infection. This review details established models for studying mucormycosis pathogenesis and evaluating treatments.

Keywords:
Caenorhabditis elegansGalleria mellonellainfection modelsmouse modelsmucoralesmucormycosispathogenesis

More Related Videos

The Arteriovenous AV Loop in a Small Animal Model to Study Angiogenesis and Vascularized Tissue Engineering
08:53

The Arteriovenous AV Loop in a Small Animal Model to Study Angiogenesis and Vascularized Tissue Engineering

Published on: November 2, 2016

13.0K
Collection and Processing of Lymph Nodes from Large Animals for RNA Analysis: Preparing for Lymph Node Transcriptomic Studies of Large Animal Species
12:53

Collection and Processing of Lymph Nodes from Large Animals for RNA Analysis: Preparing for Lymph Node Transcriptomic Studies of Large Animal Species

Published on: May 19, 2018

28.6K

Related Experiment Videos

Last Updated: Jan 27, 2026

Computer-Generated Animal Model Stimuli
26:43

Computer-Generated Animal Model Stimuli

Published on: July 29, 2007

11.3K
The Arteriovenous AV Loop in a Small Animal Model to Study Angiogenesis and Vascularized Tissue Engineering
08:53

The Arteriovenous AV Loop in a Small Animal Model to Study Angiogenesis and Vascularized Tissue Engineering

Published on: November 2, 2016

13.0K
Collection and Processing of Lymph Nodes from Large Animals for RNA Analysis: Preparing for Lymph Node Transcriptomic Studies of Large Animal Species
12:53

Collection and Processing of Lymph Nodes from Large Animals for RNA Analysis: Preparing for Lymph Node Transcriptomic Studies of Large Animal Species

Published on: May 19, 2018

28.6K

Area of Science:

  • Mycology
  • Infectious Diseases
  • Animal Modeling

Background:

  • Mucormycosis is a rare, life-threatening fungal infection caused by diverse fungi.
  • Understanding mucormycosis pathogenesis and treatment requires effective research models.
  • Animal models have historically played a critical role in advancing knowledge of fungal infections.

Purpose of the Study:

  • To review established animal models for mucormycosis.
  • To summarize the application of these models in studying mucormycosis.
  • To discuss the strengths and weaknesses of various animal model systems.

Main Methods:

  • Literature review of established animal models for mucormycosis.
  • Analysis of studies utilizing animal models to investigate mucormycosis pathogenesis.
  • Comparative assessment of different animal model systems based on reported advantages and limitations.

Main Results:

  • Several animal models, including murine, rabbit, and non-human primate models, have been developed for mucormycosis.
  • These models have elucidated key aspects of mucormycosis pathogenesis, such as fungal entry, angioinvasion, and immune responses.
  • Different models offer varying degrees of physiological relevance and experimental tractability for studying specific facets of the infection.

Conclusions:

  • Animal models are indispensable tools for dissecting the complexities of mucormycosis.
  • The choice of animal model significantly impacts the insights gained into pathogenesis and therapeutic efficacy.
  • Continued development and refinement of animal models are crucial for combating mucormycosis.