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Related Concept Videos

Schizophrenia01:17

Schizophrenia

856
Schizophrenia, a term introduced by Swiss psychiatrist Eugen Bleuler in 1911, describes a severe psychological disorder marked by profound disruptions in attention, thought processes, language, emotion, and interpersonal relationships. The core feature of schizophrenia is psychosis — a state characterized by a fundamental detachment from reality. This disconnection manifests through distorted logic, impaired perception, and atypical behavior, severely affecting the lives of those...
856
Biological Causes of Schizophrenia01:29

Biological Causes of Schizophrenia

551
Schizophrenia, a severe psychiatric disorder, arises from a complex interplay of biological factors, including genetic predisposition, structural brain abnormalities, neurotransmitter dysregulation, and developmental irregularities. These factors collectively contribute to the onset and progression of the disorder, which typically manifests in late adolescence or early adulthood.
Genetic Factors in Schizophrenia
The genetic basis of schizophrenia is strongly supported by family and twin...
551
Psychological and Sociocultural Causes of Schizophrenia01:29

Psychological and Sociocultural Causes of Schizophrenia

516
Schizophrenia, a complex psychiatric disorder, has been historically misunderstood. Early psychological theories attributed its origins to childhood trauma and unresponsive parenting. However, contemporary research largely rejects these notions, favoring the vulnerability-stress hypothesis. This model proposes that individuals with a genetic predisposition to schizophrenia may develop the disorder following exposure to significant environmental stressors. Notably, studies on high-risk...
516
Negative and Cognitive Symptoms of Schizophrenia01:30

Negative and Cognitive Symptoms of Schizophrenia

528
Negative symptoms of schizophrenia indicate a reduction or absence of typical behaviors and emotional responses found in healthy individuals, while positive symptoms reflect an excess or distortion of normal functioning.
Negative Symptoms
Negative symptoms of schizophrenia manifest as deficits in normal emotional and behavioral functioning, profoundly impacting daily life. Individuals with schizophrenia often display a flat affect, characterized by a near-total absence of emotional expression,...
528
Positive Symptoms Schizophrenia: Hallucinations and Delusions01:26

Positive Symptoms Schizophrenia: Hallucinations and Delusions

538
Schizophrenia is a complex psychiatric disorder characterized by a range of symptoms that significantly impact cognition, behavior, and emotional regulation. Among these, the positive symptoms stand out as they involve the addition or exaggeration of normal mental functions, deviating markedly from typical behavior and perception. Hallucinations and delusions are prominent positive symptoms, each profoundly affecting the individual's experience of reality.
Hallucinations
Hallucinations in...
538
Positive Symptoms of Schizophrenia: Hallucinations and Delusions01:30

Positive Symptoms of Schizophrenia: Hallucinations and Delusions

602
Schizophrenia is a complex mental health disorder that can manifest with various positive symptoms, including thought, movement, and behavior disorders. These symptoms significantly disrupt cognitive and motor functions, leading to profound effects on an individual's ability to engage with the world.
Thought Disorders
Disorganized and unusual thought processes mark thought disorders in schizophrenia. One key feature is disorganized speech, where an individual's conversation includes...
602

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[Very early onset schizophrenia].

D Da Fonseca1, P Fourneret2

  • 1Service de psychiatrie infanto-juvénile, hôpital Salvator, assistance publique, hôpitaux de Marseille, France; Institut de neurosciences de la Timone, CNRS et université d'Aix-Marseille, France.

L'Encephale
|April 3, 2019
PubMed
Summary
This summary is machine-generated.

Very early onset schizophrenia, beginning before age 13, presents diagnostic challenges due to overlapping symptoms with other disorders. Early diagnosis and multidisciplinary intervention are crucial for improving the poor prognosis of this severe neurodevelopmental disorder.

Keywords:
ChildDiagnosisDiagnosticDiagnostic différentielDifferential diagnosisEnfantSchizophrénie à début très précoceVery early onset schizophrenia

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Area of Science:

  • Child and Adolescent Psychiatry
  • Neurodevelopmental Disorders
  • Schizophrenia Spectrum Disorders

Background:

  • Very early onset schizophrenia (VEOS) is defined as schizophrenia beginning before the age of 13.
  • VEOS is exceptionally challenging to diagnose, with psychotic signs often mistaken for transient symptoms or indicative of anxiety or depressive disorders.
  • Differential diagnosis is further complicated by potential overlap with autistic spectrum disorder and frequent co-occurring conditions.

Purpose of the Study:

  • To highlight the diagnostic complexities of very early onset schizophrenia.
  • To underscore the neurodevelopmental origins of VEOS, involving genetic and environmental interactions.
  • To emphasize the critical role of early detection and intervention in managing this severe schizophrenia subtype.

Main Methods:

  • This study is a review of the literature on very early onset schizophrenia.
  • Analysis of diagnostic criteria and differential diagnoses for VEOS.
  • Examination of the neurodevelopmental aspects and prognostic factors associated with VEOS.

Main Results:

  • VEOS presents significant diagnostic hurdles due to non-specific or transient psychotic symptoms.
  • The condition is characterized by premature cerebral anomalies resulting from gene-environment interactions.
  • A continuum exists between VEOS and adult-onset schizophrenia, with VEOS representing a more severe manifestation.

Conclusions:

  • Very early onset schizophrenia is a severe neurodevelopmental disorder with a generally poor prognosis.
  • Accurate and timely diagnosis is paramount for effective management.
  • Prompt, multidisciplinary interventions significantly influence the outcome for affected children.