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Updated: Jan 27, 2026

Rapid One-step Enzymatic Synthesis and All-aqueous Purification of Trehalose Analogues
Published on: February 17, 2017
Control of meristem determinacy by trehalose 6-phosphate phosphatases is uncoupled from enzymatic activity
Hannes Claeys1, Son Lang Vi1,2, Xiaosa Xu1
1Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, NY, USA.
Abstract:
Meristem fate is regulated by trehalose 6-phosphate phosphatases (TPPs), but their mechanism of action remains mysterious. Loss of the maize TPPs RAMOSA3 and TPP4 leads to reduced meristem determinacy and more inflorescence branching. However, analysis of an allelic series revealed no correlation between enzymatic activity and branching, and a catalytically inactive version of RA3 complements the ra3 mutant. Together with their nuclear localization, these findings suggest a moonlighting function for TPPs.
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