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Correction: Functional specific roles of FADD: comparative proteomic analyses from knockout cell lines
Hongqin Zhuang1, Ziyi Gan1, Weiwei Jiang1
1The State Key Laboratory of Pharmaceutical Biotechnology, College of Life Science and School of Stomatology, Affiliated Stomatological Hospital, Nanjing University, Nanjing 210093, Jiangsu, P. R. China. hzc1117@nju.edu.cn.
Molecular Omics
|April 3, 2019
Summary
This correction clarifies the functional roles of FADD (FAS-associated death domain) protein. Proteomic analyses in knockout cell lines revealed specific FADD functions in cellular processes.
Area of Science:
- Molecular Biology
- Cell Biology
- Proteomics
Background:
- The FAS-associated death domain (FADD) protein is a critical adaptor protein in apoptosis and other cellular signaling pathways.
- Understanding the specific functional roles of FADD is essential for deciphering complex cellular mechanisms.
Purpose of the Study:
- To provide a correction and clarification regarding the functional specific roles of FADD.
- To present revised findings from comparative proteomic analyses conducted in FADD knockout cell lines.
Main Methods:
- Comparative proteomic analysis was employed.
- Experiments utilized FADD knockout cell lines to investigate protein expression changes.
Main Results:
- The correction addresses specific findings related to FADD's involvement in cellular pathways.
- Revised proteomic data highlights previously uncharacterized functions of FADD.
Conclusions:
- The corrected findings enhance the understanding of FADD's multifaceted roles in cellular signaling.
- This work provides a more accurate foundation for future research on FADD and related pathways.
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