Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Classification of Skeletal Muscle Fibers01:48

Classification of Skeletal Muscle Fibers

59.5K
Skeletal muscles continuously produce ATP to provide the energy that enables muscle contractions. Skeletal muscle fibers can be categorized into three types based on differences in their contraction speed and how they produce ATP, as well as physical differences related to these factors. Most human muscles contain all three muscle fiber types, albeit in varying proportions.
Slow-Twitch Muscle Fibers
Slow oxidative, muscle fibers appear red due to large numbers of capillaries and high levels of...
59.5K
Relaxation of Skeletal Muscles01:29

Relaxation of Skeletal Muscles

5.7K
The period of muscle contraction primarily influences the duration of stimulation at the neuromuscular junction (NMJ), the presence of free calcium ions in the sarcoplasm, and the availability of energy or ATP to support contractions.
When an action potential reaches the axon terminal, it depolarizes the membrane and opens voltage-gated sodium channels. Sodium ions enter the cell, further depolarizing the presynaptic membrane. This depolarization causes voltage-gated calcium channels to open....
5.7K
Overview of Skeletal Muscle01:15

Overview of Skeletal Muscle

14.4K
Skeletal muscles are composed of a bundle of muscle fibers and are attached to bones through tendons. Each skeletal muscle fiber is a single muscle cell. The sarcolemma, the plasma membrane of a skeletal muscle cell, consists of a lipid bilayer and glycocalyx that supports muscle fibers. The sarcolemma extends into the muscle cells to form tubular structures called transverse or T-tubules. Each side of the T-tubules consists of a membrane-bound structure called the sarcoplasmic reticulum,...
14.4K
Skeletal Muscle Anatomy00:55

Skeletal Muscle Anatomy

92.7K
Skeletal muscle is the most abundant type of muscle in the body. Tendons are the connective tissue that attaches skeletal muscle to bones. Skeletal muscles pull on tendons, which in turn pull on bones to carry out voluntary movements.
92.7K
Disorders of the Skeletal Muscle01:28

Disorders of the Skeletal Muscle

1.8K
The clinical conditions affecting the skeletal muscle tissue are broadly categorized as musculoskeletal and neuromuscular disorders.
Musculoskeletal disorders
Musculoskeletal disorders involve injuries and conditions affecting the skeletal muscles and associated connective tissues. These disorders can arise from acute biomechanical stresses or chronic overuse and can occur across different age groups. Common injuries include sprains, fractures, and muscular strains, often resulting from...
1.8K
Naming Skeletal Muscles01:19

Naming Skeletal Muscles

4.0K
The naming of the approximately 700 muscles in the human body is based on a set of criteria designed to provide descriptive information about each muscle, making it easier to identify and remember them.
The key factors used in naming muscles include:
4.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Improved metabolic stability in iNOS knockout mice with Lactobacillus supplementation.

Nutrition research (New York, N.Y.)·2024
Same author

A methionine-choline-deficient diet induces nonalcoholic steatohepatitis and alters the lipidome, metabolome, and gut microbiome profile in the C57BL/6J mouse.

Biochimica et biophysica acta. Molecular and cell biology of lipids·2024
Same author

Effect of herbal extracts and Saroglitazar on high-fat diet-induced obesity, insulin resistance, dyslipidemia, and hepatic lipidome in C57BL/6J mice.

Heliyon·2023
Same author

Comparative profiling of gut microbiota and metabolome in diet-induced obese and insulin-resistant C57BL/6J mice.

Biochimica et biophysica acta. Molecular cell research·2023
Same author

Google Trend Analysis and Paradigm Shift of Online Education Platforms during the COVID-19 Pandemic.

Infectious disease reports·2021
Same author

SET1/MLL family of proteins: functions beyond histone methylation.

Epigenetics·2020

Related Experiment Video

Updated: Jan 26, 2026

Isolation of Type I and Type II Pericytes from Mouse Skeletal Muscles
10:07

Isolation of Type I and Type II Pericytes from Mouse Skeletal Muscles

Published on: May 26, 2017

9.5K

Pericytes in Skeletal Muscle.

Jyoti Gautam1, Yao Yao2

  • 1Department of Pharmaceutical and Biomedical Sciences, University of Georgia, Athens, GA, USA.

Advances in Experimental Medicine and Biology
|April 3, 2019
PubMed
Summary

Pericytes, cells with myogenic potential, offer advantages for cell therapy in muscle disorders. Understanding their functions is key to developing innovative treatments for conditions like muscular dystrophy.

Keywords:
AdipogenesisChondrogenesisDifferentiationFibrosisMesoangioblastsMuscle injuryMuscle regenerationMuscular dystrophyMyogenesisOssificationOsteogenesisPericytesSatellite cells

More Related Videos

Mitochondrial Isolation from Skeletal Muscle
09:45

Mitochondrial Isolation from Skeletal Muscle

Published on: March 30, 2011

29.6K
Adult and Embryonic Skeletal Muscle Microexplant Culture and Isolation of Skeletal Muscle Stem Cells
14:36

Adult and Embryonic Skeletal Muscle Microexplant Culture and Isolation of Skeletal Muscle Stem Cells

Published on: September 21, 2010

29.3K

Related Experiment Videos

Last Updated: Jan 26, 2026

Isolation of Type I and Type II Pericytes from Mouse Skeletal Muscles
10:07

Isolation of Type I and Type II Pericytes from Mouse Skeletal Muscles

Published on: May 26, 2017

9.5K
Mitochondrial Isolation from Skeletal Muscle
09:45

Mitochondrial Isolation from Skeletal Muscle

Published on: March 30, 2011

29.6K
Adult and Embryonic Skeletal Muscle Microexplant Culture and Isolation of Skeletal Muscle Stem Cells
14:36

Adult and Embryonic Skeletal Muscle Microexplant Culture and Isolation of Skeletal Muscle Stem Cells

Published on: September 21, 2010

29.3K

Area of Science:

  • Biomedical Science
  • Cell Biology
  • Regenerative Medicine

Background:

  • Skeletal muscle regeneration is a complex process involving numerous cellular and molecular pathways.
  • Satellite cells (SCs) are the primary cells for muscle regeneration.
  • Pericytes exhibit significant myogenic potential and offer therapeutic advantages for muscular disorders.

Purpose of the Study:

  • To introduce the structure, marker expression, origin, and classification of pericytes.
  • To discuss the functions of pericytes in muscular dystrophy and muscle injuries.
  • To explore the myogenic, adipogenic, fibrogenic, chondrogenic, and osteogenic activities of pericytes.

Main Methods:

  • Review of existing literature on pericyte biology and function.
  • Analysis of pericyte roles in skeletal muscle regeneration and disease models.
  • Synthesis of information regarding pericyte differentiation potential.

Main Results:

  • Pericytes possess diverse differentiation capabilities beyond muscle regeneration.
  • Pericyte functions are implicated in the pathology and potential treatment of muscular dystrophy and muscle injuries.
  • Detailed characterization of pericyte attributes relevant to cell therapy.

Conclusions:

  • Understanding pericyte biology is crucial for advancing cell-based therapies for muscle disorders.
  • Pericytes represent a promising cell source for treating muscular dystrophy and other muscle-related conditions.
  • Further research into pericyte mechanisms can drive innovation in regenerative medicine for skeletal muscle.