Related Experiment Video
Updated: Jan 26, 2026

Extraction and Analysis of Taiwanese Green Propolis
Published on: January 7, 2019
New Δ-tocotrienol derivatives from Colombian propolis
Milena P Popova1, Boryana S Trusheva1, Paraskev T Nedialkov2
1Institute of Organic Chemistry with Centre of Phytochemistry Bulgarian Academy of Sciences , Sofia , Bulgaria.
Abstract:
Two new δ-tocotrienol derivatives with oxidized terminal chain: 5,6-dioxo-garcinoic acid (trans-13'-carboxy-5,6-dioxo-δ-tocotrienol) (2) and 5-hydroxy-8b-oxo garcinoic acid (trans-13'-carboxy-5-hydroxy-8b-oxo-δ-tocotrienol) (3), together with one known derivative garcinoic acid (trans-13'-carboxy-δ-tocotrienol) (1) were isolated from a Colombian propolis. Garcinoic acid was found as a propolis constituent for the first time. The isolated compounds and crude ethanolic extract demonstrated high antimicrobial activity against Staphylococcus aureus and Candida albicans (MICs range: 10-39 μg/ml) as well as promising antioxidant potential in DPPH assay. Compound 3 displayed highest radical scavenging activity, even higher than that of dl-α-tocopherol, used as a positive control.
Related Concept Videos
Measurement: Derived Units
Free Energy and Equilibrium
Recall that Q is the numerical value of the mass action...
First Derivative Test: Problem Solving
Second Derivative Test: Problem Solving
Derivatives of the Trigonometric Functions
Derivatives of Logarithmic Functions

