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Updated: Jan 26, 2026

Thermal Measurement Techniques in Analytical Microfluidic Devices
Published on: June 3, 2015
Thermal Resistance of Paralytic Shellfish Poison in Soft-Shell Clams
T A Gill1, J W Thompson1, S Gould1
1Canadian Institute of Fisheries Technology, Technical University of Nova Scotia, P.O. Box 1000, Halifax, Nova Scotia, B3J 2X4, Canada.
Abstract:
Toxic soft-shell clams ( Mya arenaria ) were collected and the meats homogenized and tested for toxicity by the A.O.A.C. mouse bioassay procedure. The homogenate was incubated at temperatures ranging from 220 to 269.5°F and toxicities measured in samples heated for various time intervals. The relationships between toxicity and the time of heating were semilogarithmic for each of the six incubation temperatures. Decimal reduction times were calculated for each heat treatment and were plotted (log scale) against heating temperature. The thermal-destruction-time (TDT) curve was linear (r2 = 0.97), indicating that the kinetics of paralytic shellfish poison destruction are similar to those of most microorganisms. The toxin levels were also analyzed by high performance liquid chromatography for 110 samples and although results compared favorably with the bioassay data, its reliability for routine assessment of toxicity was not clearly established.
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