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Spirometry reference equations for an adult Middle Eastern population.

Walid Al-Qerem1, Alaa M Hammad1, Ezeddin S Gassar1

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This study establishes crucial spirometric reference values for healthy Jordanian adults. These findings aid in accurate diagnosis and management of respiratory diseases in the Middle East.

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Area of Science:

  • Pulmonary Medicine
  • Clinical Physiology

Background:

  • Spirometric reference values are essential for diagnosing and monitoring respiratory conditions.
  • Accurate interpretation of lung function tests requires population-specific data.
  • Existing spirometric data may not accurately represent the Jordanian population.

Purpose of the Study:

  • To determine spirometric reference values for a healthy Jordanian adult population.
  • To provide a basis for precise interpretation of spirometry results in Jordan.
  • To contribute to respiratory health assessment in the Middle East.

Main Methods:

  • Recruitment of participants from various healthcare settings and a university in Jordan.
  • Utilisation of generalised additive models for location scale and shape (GAMLSS) for data analysis.
  • Derivation of spirometric reference values from a large cohort of healthy, non-smoking adults.

Main Results:

  • Spirometric reference values were derived from 1,949 healthy non-smoking adults (1,061 females).
  • The derived values were validated using a separate group of 300 healthy non-smoking subjects (150 females).
  • The study successfully generated spirometric reference values tailored for Jordanian adults.

Conclusions:

  • Developed spirometric reference values specific to the Jordanian population.
  • These values are applicable to the broader Middle Eastern adult population.
  • Facilitates improved clinical decision-making in respiratory medicine within the region.