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Updated: Jan 26, 2026

Activation and Measurement of NLRP3 Inflammasome Activity Using IL-1β in Human Monocyte-derived Dendritic Cells
Published on: May 22, 2014
[Corrigendum] NLRP3 inflammasome is responsible for Hantavirus inducing interleukin‑1β in THP‑1 cells
Wei Ye1, Yingfeng Lei1, Mengmeng Yu2
1Department of Microbiology, The Fourth Military Medical University, Xi'an, Shaanxi 710032, P.R. China.
Abstract:
Subsequently to the publication of the above article, the authors have realized that an error was introduced in the preparation of Fig. 2B for publication. In Fig. 2B, the lanes shown for the western blot were misannotated. Additionally, in the legend of Fig. 2C, '24 h post‑infection' should have been written as '12 h post‑infection'. Furthermore, the description of the data shown in Fig. 2B in the Results section (sentence commencing on p. 1635, the subsection 'HTNV activates caspase‑1 and pro‑IL‑1β in THP‑1 cells', line 10), was incomplete. The sentence here should have read as follows (the added text is highlighted in bold): 'In order to investigate whether caspase‑1 was activated during HTNV infection, the culture supernatant of HTNV‑infected THP‑1 was ultra‑filtered and an increased concentration of secreted caspase‑1 was detected post‑infection compared with the Mock group; similar results were also observed in the LPS‑ and ATP‑stimulated groups (Fig. 2B)'. The correct version of Fig. 2, with the lanes of the western blot in Fig. 2B labelled correctly and the appropriate changes having been made to the Figure legend, is shown opposite. The errors associated with this Figure did not have an impact on the overall meaning of the paper, or on the reported conclusions of this study. The authors regret that this Figure was not corrected prior to the publication of this article, and apologize to the readership for any inconvenience caused. [the original article was published in International Journal of Molecular Medicine 35: 1633‑1640, 2015; DOI: 10.3892/ijmm.2015.2162].
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